ObjectiveTo evaluate the prevalence of burnout syndrome among nursing workers in intensive care units and establish associations with psychosocial factors.MethodsThis descriptive study evaluated 130 professionals, including nurses, nursing technicians, and nursing assistants, who performed their activities in intensive care and coronary care units in 2 large hospitals in the city of Rio de Janeiro, Brazil. Data were collected in 2011 using a self-reported questionnaire. The Maslach Burnout Inventory was used to evaluate the burnout syndrome dimensions, and the Self Reporting Questionnaire was used to evaluate common mental disorders.ResultsThe prevalence of burnout syndrome was 55.3% (n = 72). In the quadrants of the demand-control model, low-strain workers exhibited a prevalence of 64.5% of suspected cases of burnout, whereas high-strain workers exhibited a prevalence of 72.5% of suspected cases (p = 0.006). The prevalence of suspected cases of common mental disorders was 27.7%; of these, 80.6% were associated with burnout syndrome (< 0.0001). The multivariate analysis adjusted for gender, age, educational level, weekly work duration, income, and thoughts about work during free time indicated that the categories associated with intermediate stress levels - active work (OR = 0.26; 95%CI = 0.09 - 0.69) and passive work (OR = 0.22; 95%CI = 0.07 - 0.63) - were protective factors for burnout syndrome.ConclusionPsychosocial factors were associated with the development of burnout syndrome in this group. These results underscore the need for the development of further studies aimed at intervention and the prevention of the syndrome.

Background: Preemptive analgesia has as its basic principle the administration of analgesics before the onset of painful stimuli, in order to reduce or prevent postoperative pain, but this question is little explored in implantology. Thus, this study was conducted in order to evaluate the clinical efficacy of ibuprofen in pain prevention after unit implant surgery. Material and Methods: For this triple-blind, parallel, placebo-controlled and randomized clinical trial, 54 insertion surgeries of unitary implants were performed. Two groups have received two different protocols 1 hour before surgery: Ibuprofen group (IBU) 600 mg of ibuprofen; and (2) placebo group (maize starch). The intensity of the pain was evaluated through the visual analogue scale (VAS) in 6 times (1, 6, 12, 24, 48 and 72 hours after the surgery). Patients were instructed to take 750 mg of paracetamol as rescue medication, if necessary. The occurrence and the intensity of pain were analyzed by means of an analysis of variance ANOVA with repeated measurements using the general linear model procedure. Results: The IBU group had significantly lower VAS scores overall (IBU = 0.30, ± 0.57; placebo = 1.14, ± 1.07; p<0.001) and at all times in the intra, intergroup comparisons and time/group interaction than the placebo group (p< 0.001). The use of rescue medication was significantly lower and the postoperative time was longer in the IBU group compared to placebo (p = 0.002). Conclusions: The single use of ibuprofen was found to be significantly superior in reducing pain after unit implant surgery compared to placebo.

Abstract

A reemergência do dengue no Brasil é resultante da recente reinfestação do país pelo mosquito Aedes (Stegomyia) aegypti Linnaeus, 1762 (Diptera: Culicidae), principal transmissor do dengue e também responsável pela transmissão da febre amarela urbana 3 9. Minas Gerais está entre os estados com maior incidência de dengue e a Cidade de Uberlândia contribui significativamente com estes números 4 . A luta antivetorial tem sido a principal estratégia de controle desta doença tanto no Brasil, quanto nos demais países atingidos por esta arbovirose.Embora a biologia deste mosquito seja razoavelmente bem conhecida, peculiaridades regionais e locais relacionadas ao clima e às modificações do ambiente feitas pelo ser humano interferem na dinâmica populacional do mosquito ao longo do ano. Assim, o conhecimento dessas particularidades é fundamental para a aplicação de medidas de controle mais efetivas regional e localmente.Coletas com auxílio de armadilhas de oviposição (ovitrampas) apresentam alta sensibilidade, permitem detectar a presença e estimar a abundância relativa deste díptero, adequando-se para uso em estudos em campo e na vigilância vetorial deste culicídeo ABSTRACTAspects of the population dynamics of Aedes aegypti were investigated from collections over a two-year period in the urban area of Uberlândia, State of Minas Gerais. The population dynamics of this mosquito were influenced by physical factors such as temperature and rainfall. High larval densities also had an influence on mosquito development.

O Sars-CoV-2, Coronavírus ou COVID-19, é uma síndrome respiratória de espectro viral evidenciada pela primeira vez em dezembro de 2019 em Wuhan, China. Por ser ainda um vírus pouco conhecido e com potencial letal, a população busca encontrar uma solução rápida e fácil para a doença, como a prática da automedicação. Objetou-se escrever os fatores que corroboram para a prática da automedicação em período de pandemia de COVID-19. Trata-se de uma revisão integrativa da literatura, onde a construção do estudo sustentou-se na pergunta “Quais os fatores que corroboram para a prática da automedicação em período de pandemia de COVID-19?”. O levantamento bibliográfico foi realizado no mês de fevereiro de 2021, utilizando as bases de dados Medline, PubMed, Redib e Scielo através dos descritores “Automedicação”, “Infecções por Coronavírus”, “Educação em Saúde”. Após os critérios de inclusão e exclusão, restaram 6 artigos com perfil adequado para a produção desse estudo. Os artigos evidenciaram que a automedicação foi impulsionada no período de pandemia, sendo utilizadas tanto para prevenção como tratamento da COVID-19. O uso irracional de medicamentos tomou frente, por conta dos supostos tratamentos relacionados com a COVID-19.

Funding informationCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) of the Brazilian Ministry of Education The canine BRCA2 is a tumor supressor gene which encodes the BRCA2 protein, involved in DNA repair through interaction with the RAD51 recombinase. This process is mediated by eigth BRC repeats that are encoded by BRCA2 exon 11. Two variants corresponding to human mutations in human BRC3 repeat have been reported in canine BRC3 repeat. In addition, other variants have also been described in canine BRCA2 exon 11. Considering the importance of polymorphisms in human BRCA2 to breast cancer development, this study aimed to investigate the frequency of variants in BRCA2 exon 11 in 48 blood and tissue DNA samples from bitches with canine mammary tumors (CMT), as well as, to analyze tumor stage and histopathological features. Seven Single Nucleotide Polymorphisms (SNPs) were identified, three of which were evaluated as possibily or probably deleterious variant.Interestingly, almost all the 22 mammary tumors (except one) which presented a clinical staging equal to or greater than III carried at least one mutant allele of these three variants.Besides that, no statistically significant correlation was observed between any of the reported SNPs in heterozygosis or homozygosis and either dogs data (such as breed, age or disease stage) or mammary tumors histopathological characteristics. A total of 97.9% of bitches had one to three polymorphisms of the seven identified in this study, which suggests a possibly correlation between the canine BRCA2 exon 11 polymorphisms and mammary carcinogenesis. K E Y W O R D SBRCA2, breast cancer, canine, carcinogenesis, RAD51

The bedbugs Cimex lectularius and Cimex hemipterus are obligate hematophages in all their nymphal instars as well as in the adult stage. The efficiency with which the insects obtain blood from their hosts is directly related to their population dynamics. In the present study we compared the feeding process and salivary content in individuals of these two species when fed on different blood sources or host sites, using a cibarial pump electromyogram. Females ingested more blood than males but needed longer contact time with the host to complete the meal. The bedbug C. lectularius was more efficient than C. hemipterus in obtaining blood from mice and pigeons. With regard to the feeding site on mice, it was easier for the insects to obtain blood from the skin of the belly than that of the back. Individuals of C. hemipterus were able to maintain the cibarial pump functioning at higher frequencies for longer periods when fed on pigeons treated with anticoagulant. Although saliva from C. lectularius contained more hemeproteins and showed more anti-clotting activity its total protein content was similar to that of C. hemipterus. Overall, C. lectularius obtains a bloodmeal more efficiently from its hosts, which may have enabled this species to reach higher levels of infestation than C. hemipterus.

Background Periodontal disease may be associated with more bacteria and consequent induction of a systemic inflammatory process, with changes in the levels of C-reactive protein (CRP). The purpose of this cross-sectional study was to evaluate the association between periodontitis and serum levels of C-reactive protein. Material and Methods The sample comprised 100 individuals distributed into two groups according to serum levels of C-reactive protein: normal or altered. Social, biological and behavioral data were collected by means of a structured questionnaire. Additionally, a blood test was requested to measure C-reactive protein levels. CRP values less than 3 mg/l were considered normal. Periodontal clinical examination was conducted in each participant for analysis of probing depth, bleeding on probing and clinical attachment level. Descriptive statistics, univariate analysis and logistic regression were performed. Results were provided in odds ratio, confidence intervals and p values. Results Individuals with altered C-reactive protein levels showed a higher prevalence of periodontitis than individuals with normal C-reactive protein levels ( p =0.008). In the final logistic regression model, individuals with periodontitis were more likely to present altered C-reactive protein than individuals without periodontitis (OR=3.27, CI=1.42-7.52, p =0.005). Conclusions The alteration of the C-reactive protein levels among individuals with a higher prevalence of periodontitis corroborates clinical evidence that periodontal infection has a systemic impact. Key words: C-reactive protein, cytokines, periodontal diseases, periodontitis.