Aim. The aim of this study was to see the clinical, pathological, and demographic profile of young patients with stomach carcinoma besides association with p53. Patients and Methods. Prospective study of young patients with stomach carcinoma from January 2005 to December 2009. A total of 50 patients with age less than 40 years were studied. Results. Male female ratio was 1 : 1.08 in young patients and 2.5 : 1 in older patients. A positive family history of stomach cancer in the first degree relatives was present in 10% of young patients. Resection was possible only in 50% young patients. 26% young patients underwent only palliative gastrojejunostomy. The most common operation was lower partial gastrectomy in 68%. Amongst the intraoperative findings peritoneal metastasis was seen in 17.4% in young patients. 50% young patients presented in stage IV as per AJCC classification (P value .004; sig.). None of the patients presented as stage 1 disease in young group. Conclusion. Early detection of stomach carcinoma is very important in all patients but in young patients it is of paramount importance.

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Terminal ileal perforation should be suspected in all cases of peritonitis especially in developing countries and surgical treatment should be optimized taking various accounts like etiology, delay in surgery and operative findings into consideration to reduce the incidence of deadly complications like fecal fistula.

AMAÇAyaklanan grupların kontrol edilirken uğradıkları saçma ile silah yaralanmaları incelendi. GEREÇ VE YÖNTEMSaçma tanesi ile gerçekleşen silah yaralanmaları nedeniyle kaza ve acil servis bölümüne yatırılan toplam 198 hasta, anatomik bölge, ciddiyet ile yaralanma tipi, tedavi ve sonuçlar bakımından değerlendirildi. BULGULARHastaların %72,7'si, 16 ile 25 yaş arasında idi. En sık yaralanma bölgeleri ekstremiteler (%47,9), karın (%36,3) ve göğüs (%31,3) idi. Hastaların %59,5'inde minör yaralanma vardı. Yaralanmaları nedeniyle hastaneye yatırılan 80 hastanın 43'ü (%53,7) ameliyat edildi. Altı adet ölüm (%3,03) gözlemlendi. SONUÇKendi başına saçma yaraları önemsiz gibi görünebilir, ancak, kafaya, göğüse ve karına yönelik potansiyel doku hasarına neden olabilecek yaralanmaların değerlendirilme-mesi durumunda ölümcül sonuçlar ortaya çıkabilir. Hastalar, genel kurşun yaralanmaları ile aynı şekilde değerlendi-rilmeli ve tedavi edilmelidir.Anahtar Sözcükler: Saçma yaraları, barutsuz silahlar.

Prophylactic use of subcutaneous drains in obese patients undergoing cholecystectomy was found to reduce the seroma formation significantly.

The aim of this study was to investigate the role of the XRCC1 Arg399Gln polymorphism in the susceptibility of a Kashmiri population to colorectal cancer (CRC). We investigated the genotype distribution of the XRCC1 gene in 130 CRC cases in comparison with that of 150 healthy subjects. There was no direct significant association between the XRCC1 genotypes and CRC; however, the Arg/Gln genotype was associated with an elevated risk of CRC (OR>1.47) and the Gln/Gln variant genotype was associated with an increased risk of CRC in various clinicopathological parameters. This study suggests that the XRCC1 polymorphism is associated with an increased risk of CRC.

This is a case report of a young man who presented to us as a case of hypogastric pain and frequency of micturation. General physical examination and radiological evaluation confirmed a multiloculated pelvic swelling. Patient was subjected to laparotomy which confirmed the diagnosis of a primary pelvic hydatid disease. Patient was put on chemotherapy after surgery and is doing well on follow up.

BackgroundPrimary squamous cell carcinomas of the colorectum are very uncommon. Until now, to the best of our knowledge, only 114 cases of squamous cell carcinoma in the colorectum exist in the reported literature. Here we report a case of squamous cell carcinoma of the rectum in the ethnic Kashmiri population in northern India.Case PresentationThe case of a 60-year-old male patient (Asian) with a pure squamous cell carcinoma of the rectum is presented here. The patient underwent a curative surgery with concomitant chemotherapy. Two years after the initial curative resection of the tumor he is still alive.ConclusionThe prognosis for squamous cell carcinoma of the colorectum is worse than for that of adenocarcinoma, because of the delayed diagnosis. The etiopathogenicity of squamous cell carcinoma of the colorectum is discussed. Surgical resection of the lesion seems to be the treatment of choice. Chemotherapy also helps in improvement of the prognosis.