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Wani, Rauf Ahmad; Parray, Fazl Q.; Bhat, Nisar Ahmad; Wani, Mohd Yaqoob; Bhat, Tasaduq H; Farzana, Fowzia

doi:10.1186/1749-7922-1-7

Cited by 46 publications

(29 citation statements)

References 7 publications

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“…Worldwide there is a predominance of males presenting with this life-threatening disease [11,12]; our series also shows a similar trend, with a male to female ratio of 3.3:1.…”

Section: Discussionsupporting

confidence: 78%

An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan

et al. 2012

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ObjectivePeritonitis is the most common life threatening surgical emergency, which requires urgent surgical intervention and is a significant cause of morbidity and mortality. The objective of this study was to highlight the frequency of secondary peritonitis and to analyze the site and causes of perforation, in our tertiary care setup.MethodsA retrospective analysis of 311 patients of secondary peritonitis was done from July 2008 to June 2010 at Liaquat University Hospital Jamshoro, Hyderabad, Sindh, Pakistan. All cases found to have peritonitis as a result of perforation of any part of gastrointestinal tract at the time of surgery were included in the study. All cases with either primary peritonitis or that due to anastomotic dehiscence were excluded.ResultsA total of 311 patients were studied. Most of the patients were males (77%) and (89%) were in the third and fourth decades of life. Majority of the patients presented with pain (97%) associated with bowel symptoms. Most common site of perforation was small bowel (ileal 59%, jujenal 2%). In this series, most common risk factor of perforation was typhoid (43%). Ileostomy was the most commonly performed procedure. Overall morbidity was 48.5% and mortality was 17%.ConclusionConsidering the relatively higher rate of typhoid perforation quoted in this study, it is vital that typhoid fever ought to be eliminated by improved sanitation and immunizing programmes, otherwise surgeons will be confronted with its complications.

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“…Worldwide there is a predominance of males presenting with this life-threatening disease [11,12]; our series also shows a similar trend, with a male to female ratio of 3.3:1.…”

Section: Discussionsupporting

confidence: 78%

An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan

et al. 2012

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“…In literature it is usually advocated that last 60 centimeters of the ileum should be resected. However in our study various surgical techniques were performed, though mortality and morbidity remained high and most dreaded complication being fecal fistula and wound dehiscence 12,13 . Table-4.…”

Section: Discussionmentioning

confidence: 73%

“…We found small bowel obstruction as another important cause for terminal ileal perforation in our study. There were 53 cases with single perforation, 9 patients had 2 perforation and 9 had multiple perforations and all the perforations were 5 to 60 cms from ileocaecal junction along the anti mesenteric border of ileum 10,12 . Late presentation , delay in operation(>48 hours), multiple perforations and gross contamination of the peritoneal cavity with pus and fecal material affected the incidence of fecal fistula and wound dehiscence and subsequent mortality 8,9,10,11 .…”

Section: Discussionmentioning

confidence: 99%

“…Non traumatic ileal perforation may include typhoid, tuberculosis and idiopathic in nature. Delay in surgical intervention is often accompanied in rural sectors and the places where medical facilities are scarce due to lack of specific and sensitive diagnostic investigations 8,9,10,11,12 . Surgical option such as Simple/Primary closure, Resection and end to end Anastomosis, Ileotransverse anastomosis, Primary Ileostomy are commonly performed.Various factors plays a vital role in mobidity and mortality in determining the outcome measures in Nontraumatic illeal perforation such as delay in presentation, anaemia, hypovolumic shock, septicaemic shock,fecal contamination of peritoneum, age etc.…”

Section: Introductionmentioning

confidence: 99%

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Nontraumatic Ileal Perforation : Surgical Experience in Rural Population in Indian Scenario

Mohan¹,

Bhaskaran²,

Kumar³

et al. 2013

Int J of Biomed & Adv Res

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“…Noninfectious diseases such as primary small-bowel malignancies and Crohn's disease (CD) are common causes in developed countries [2,3]. Intestinal tuberculosis (ITB) and typhoid enteritis are common causes in developing countries [4,5]. Although spontaneous small-bowel perforation can be diagnosed easily using simple abdominal radiographs or CT scans of the abdomen, the differential diagnosis of its etiology is a major challenge preoperatively.…”

Section: Introductionmentioning

confidence: 99%

Differential Diagnosis of Crohn's Disease and Intestinal Tuberculosis in Patients with Spontaneous Small-Bowel Perforation

Kim¹,

Kim²,

Jeong³

et al. 2014

Dig Surg

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Background/Aims: Spontaneous small-bowel perforation caused by Crohn's disease (CD) or intestinal tuberculosis (ITB) is a rare disease entity. We investigated the clinical features and radiologic findings of patients with CD or ITB who presented with a spontaneous small-bowel perforation. Methods: Between January 2001 and December 2010, sixty-two patients underwent surgery due to a spontaneous small-bowel perforation, including 21 (33.9%) CD patients and 18 (29.0%) ITB patients. Clinical and radiologic features were compared between CD and ITB patients. Results: The mean age was significantly lower in CD patients than in ITB patients (p = 0.014). Diarrhea was more common in CD. By contrast, night sweating and a previous history of tuberculosis were more common in ITB. Only 27.8% of patients with ITB had a positive QuantiFERON-TB Gold test. CT findings such as bowel wall thickening of more than 10 mm, omental thickening, and intra-abdominal lymphadenopathy larger than 10 mm were more common among perforations caused by ITB. Mesenteric fat infiltration was a more frequent finding in CD than in ITB. Conclusions: Clinical symptoms and radiologic findings may aid in the differential diagnosis between CD and ITB in patients presenting with spontaneous small-bowel perforation.

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Cited by 46 publications

References 7 publications

An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan

An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan

Nontraumatic Ileal Perforation : Surgical Experience in Rural Population in Indian Scenario

Differential Diagnosis of Crohn's Disease and Intestinal Tuberculosis in Patients with Spontaneous Small-Bowel Perforation

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