No abstract

Abstract. The current report describes 3 rare cases of mammary diffuse fibroadenomatoid hyperplasia in water buffalo (Bubalus bubalis). All of the animals were between 10 and 12 months of age. Grossly, the lesions consisted of severe diffuse swelling with homogeneous large masses in the udder. Surgical removal of the masses was curative. Microscopically, there was severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini and their associated ducts. Moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was also evident. The hyperplastic epithelial cells exhibited positive immunostaining for cytokeratin, estrogen receptors, and progesterone receptors. In addition, the myoepithelial cells displayed moderate positivity for alpha smooth muscle actin. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary diffuse fibroadenomatoid hyperplasia with probable hormonal influence was made.

Similar to software systems, programming languages evolve substantially over time. Indeed, the community has more recently seen the release of new versions of mainstream languages in shorter and shorter time frames. For instance, the C++ working group has begun to release a new version of the language every 3 years, which now has a greater number of modern C++ features and improvements in modern standards (C++11, C++14, C++17, and C++ 20). Nonetheless, there is little empirical evidence on how developers are transitioning to use modern C++ constructs in legacy systems, and not understanding the trends and reasons for adopting these new modern C++ features might hinder software developers in conducting rejuvenation efforts. In this paper, we conduct an in‐depth study to understand the development practices of KDE contributors to evolve their projects toward the use of modern C++ features. Our results show a trend in the widespread adoption of some modern C++ features (lambda expressions, auto‐typed variables, and range‐based for) in KDE community projects. We also found that developers in the KDE community are making large efforts to modernize their programs using automated tools, and we present some modernization scenarios and the benefits of adopting modern C++ features of the C++ programming language. Our results might help C++ software developers, in general, to evolve C++ legacy systems and tools builders to implement more effective tools that could help in rejuvenation efforts.