The black yeast genus Exophiala is known to cause a wide variety of diseases in severely ill individuals but can also affect immunocompetent individuals. Virulence markers and other physiological parameters were tested in eight clinical and 218 environmental strains, with a specific focus on human-dominated habitats for the latter. Urease and catalase were consistently present in all samples; four strains expressed proteinase and three strains expressed DNase, whereas none of the strains showed phospholipase, haemolysis, or co-haemolysis activities. Biofilm formation was identified in 30 (13.8%) of the environmental isolates, particularly in strains from dishwashers, and was noted in only two (25%) of the clinical strains. These results indicate that virulence factors are inconsistently present in the investigated Exophiala species, suggesting opportunism rather than pathogenicity.

Fusarium species are fungi that are found in nature, but rarely cause infections in humans. They may lead to a variety of infections that are insignificant, locally invasive, and widespread. Some Fusarium infec

Magnusiomyces capitatus is an emerging opportunistic fungal pathogen particularly in immunocompromised patients. We report a case of a M. capitatus peritonitis in child with acute lymphocytic leukemia as a breakthrough infection during caspofungin therapy. The possibility of breakthrough infections caused by M. capitatus must be taken into consideration, particularly in immunosupressed patients being treated for systemic fungal infections by caspofungin. Although there are no defined breakpoints for susceptibility testing of M.capitatus, minimal inhibitory concentration results can be helpful for therapy. Antifungal treatment with amphotericin B lipid complex plus flucytosine can be effective against infections caused by M. capitatus.

No abstract

Kandidemi, nozokomiyal kan dolaşımı enfeksiyonları arasında dördüncü sırada yer almaktadır. İnvaziv kandidiyazda Candida albicans halen en sık tanımlanan patojen olsa da, albicans dışı kandida türlerine bağlı enfeksiyonlarda dramatik artış dikkati çekmektedir bu durum, klinik uygulamadaki değişimleri yansıtmaktadır. Bu çalışmanın temel amacı kandidemi etkeni Candida türlerinin hastanemizdeki dağılımını belirleyerek hastane enfeksiyonlarının önlenmesine katkıda bulunmaktır.Yöntemler: Retrospektif (2013Retrospektif ( -2014 bu çalışmada kan kültürlerinden izole edilen Candida türlerinin epidemiyolojik, klinik ve mikrobiyolojik karakteristikleri bildirilmiştir.