<scp>
              <i>Fusarium solani</i>
            </scp>
            infection in a diabetic patient treated with itraconazole and debridement

Karadağ, Ayşe Serap; Cebeci, Filiz; Kayıran, Melek Aslan; Özakkaş, Fatma; Çobanoğlu, Bengü; Kuru, Burçe Can; Arslan, Zeynep; Gürel, Mehmet Salih

doi:10.1111/dth.14203

Cited by 2 publications

(2 citation statements)

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“…FSSC, F. solani species complex (SC); FFSC, F. fujikuroi SC; FOSC, F. oxysporum SC; FNSC, F. nisikadoi SC; FIESC, F. incarnatum-equiseti SC; FDSC, F. dimerum SC; FCSC, F. chlamydosporum SC. 10.3389/fmicb.2022.992582 Frontiers in Microbiology 08 frontiersin.org 2006; Pai et al, 2010;Atty et al, 2014;Rosanova et al, 2016;Karadag et al, 2020;Tram et al, 2020;Liza et al, 2021). We observed 63.2% (24/38) of isolates from skin secretions belonged to FSSC.…”

Section: Discussionmentioning

confidence: 99%

“…Severe burns and poorly controlled diabetes are thought to be high risk factors for invasive mold infections ( Nucci and Anaissie, 2007 ; Enoch et al, 2017 ). However, little is known about the epidemiology of Fusarium strains causing locally invasive skin infection in patients with burns or diabetes mellitus, limited by sporadic case reports ( Nucci and Anaissie, 2002 ; Taj-Aldeen et al, 2006 ; Pai et al, 2010 ; Atty et al, 2014 ; Rosanova et al, 2016 ; Karadag et al, 2020 ; Tram et al, 2020 ; Liza et al, 2021 ). We observed 63.2% (24/38) of isolates from skin secretions belonged to FSSC.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China

et al. 2022

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BackgroundFusarium species are opportunistic causative agents of superficial and disseminated human infections. Fast and accurate identification and targeted antifungal therapy give help to improve the patients’ prognosis.ObjectivesThis study aimed to evaluate the effectiveness of matrix-assisted laser desorption ionisation time of flight mass spectrometry (MALDI-TOF MS) for Fusarium identification, and investigate the epidemiology and antifungal susceptibility profiles of clinical Fusarium isolates in Southern China.MethodsThere were 95 clinical Fusarium isolates identified by DNA sequencing of translation elongation factor 1-alpha (TEF1α) and MALDI-TOF MS, respectively. Antifungal susceptibility testing of isolates was performed by broth microdilution according to the CLSI approved standard M38-A3 document.ResultsSeven species complexes (SC) with 17 Fusarium species were identified. The most prevalent SC was the F. solani SC (70.5%, 67/95), followed by the F. fujikuroi SC (16.8%, 16/95). F. keratoplasticum within the F. solani SC was the most prevalent species (32.6%, 31/95). There were 91.6% (87/95) of isolates identified by MALDI-TOF MS at the SC level. In most of species, amphotericin B and voriconazole showed lower MICs compared to itraconazole and terbinafine. The F. solani SC showed higher MICs to these antifungal agents compared to the other SCs. There were 10.5% (10/95) of strains with high MICs for amphotericin B (≥8 μg/ml), terbinafine (≥32 μg/ml) and itraconazole (≥32 μg/ml) simultaneously, mostly focusing on F. keratoplasticum (9/10).ConclusionMALDI-TOF MS exhibited good performance on the identification of Fusarium strains at the SC level. The F. solani SC was the most prevalent clinical SC in Southern China. The MICs varied significantly among different species or SCs to different antifungal agents.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China

et al. 2022

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Fusarium oxysporum disseminated infection in a teenage patient with a relapse of acute lymphoblastic leukemia - Case report and review of the literature

Samborska,

Wziątek,

Młynarczyk

et al. 2024

Journal of Infection and Chemotherapy

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Fusarium solani infection in a diabetic patient treated with itraconazole and debridement

Abstract: Fusarium species are fungi that are found in nature, but rarely cause infections in humans. They may lead to a variety of infections that are insignificant, locally invasive, and widespread. Some Fusarium infec

Cited by 2 publications

References 5 publications

Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China

Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China

Fusarium oxysporum disseminated infection in a teenage patient with a relapse of acute lymphoblastic leukemia - Case report and review of the literature

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