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Background:The effectiveness of low power lasers on incisional wound healing, because of conflicting results of previous studies, is uncertain. Therefore, the aim of this study was to evaluate the effects of low-level helium-neon (He-Ne) laser irradiation on wound healing in rat's oral mucosa.Materials and Methods:Sixty-four standardized incisions were carried out on the buccal mucosa of 32 male Wistar divided into four groups of eight animals each. Each rat received two incisions on the opposite sides of the buccal mucosa by a steel scalpel. On the right side (test side), a He-Ne laser (632 nm) was employed on the incision for 40 s. Laser radiation was used just in 1st day, 1st and 2nd day, 1st and 3rd day, and continuous 3 days in groups of A, B, C, and D of rats, respectively. The left side (control side) did not receive any laser. Histological processing and hematoxylin and eosin staining were done on tissue samples after 5 days. Wilcoxon and Kruskal-Wallis tests were used for statistical analysis.Results:Histological analysis showed that the tissue healing after continuous 3 days on the laser irradiated side was better than the control side, but there was no difference between the two sides in each groups (P > 0.05).Conclusion:This study showed that He-Ne laser had no beneficial effects on incisional oral wound healing particularly in 5 days after laser therapy. Future research in the field of laser effects on oral wound healing in human is recommended.

Background The aim of this study was to investigate the association of denture stomatitis prevalence with cigarette, hookah and opium consumption and also dose–response relationship between the cigarette smoking duration and odds of denture stomatitis in population of Rafsanjan cohort center. Methods This cross-sectional study based on data of Rafsanjan Cohort Study (RCS) with 10,000 participants. After applying inclusion and exclusion criteria, 1619 participants were included in the analysis. Data were collected by oral examination and completion of pre-designed questionnaires to assess denture hygiene, smoking behavior, opium use and some other exposure variables. Multivariable logistic regression models were fitted to investigate possible association of cigarette, hookah and opium consumption and denture stomatitis. Results Prevalence of denture stomatitis among all 1619 denture wearers was 21.6%. Cigarette smoking was associated with a higher odds of denture stomatitis, with the adjusted odds ratio (95% CI) of 2.29 (1.53–3.41). Also, dose–response increases were observed with the highest odds ratio in the 4th quartile for denture stomatitis (p-value < 0.001). Opium consumption was associated with a decreased odds of denture stomatitis (adjusted OR; 0.81, 95% CI 0.58–1.13) which was not statistically significant. Also interaction between opium consumption and cigarette smoking was not associated with higher odds of denture stomatitis (adjusted OR: 1.65, 95% CI 0.85–3.22). Conclusions Based on the findings of the present study, while cigarette smoking had a dose–response relationship with the increased odds of denture stomatitis; this association was not found with opium consumption.

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Background: Children are the most sensitive and vulnerable group in terms of tooth decay. Any change or improvement in health-related knowledge and behavior in this group can have long-term and significant impacts on the health of the future generation. Thus, the present study was conducted with the aim to determine the relationship of knowledge of oral health-related issues with the decayed, missing, and filled teeth (DMFT) index in 12-year-old students of Rafsanjan, Iran, in 2016. Materials and Methods: This descriptive, cross-sectional study was performed on 460 students (230 boys and 230 girls) of 12 years of age from 10 elementary schools in Rafsanjan. The subjects were randomly selected. Data were collected through clinical examination, interviews, and a questionnaire. The questionnaire consisted of two parts; the first part contained a demographic characteristics form, and the second part contained the DMFT index and questions on knowledge of oral health-related issues. Data were analyzed using independent t-test, ANOVA, chi-square, and the Pearson correlation coefficient (α = 0.05). Results: Mean DMFT index and knowledge score of the students were 2.66 ± 1.40 and 5.43 ± 1.82, respectively. Students with higher knowledge had lower DMFT index. Moreover, mean knowledge score of students with homemaker mothers was significantly higher compared to students with working mothers. Conclusion: The results of this study suggested a positive significant relationship between knowledge of oral health-related issues and DMFT index in 12-year-old students of Rafsanjan.

Salvadora persica (S. persica), Meswak, is an evergreen shrub to 6-7 m. It has many biological activities such as antipyretic, anti-inflammatory and antifungal activities. This study evaluated in vitro cytotoxic and anti-inflammatory effects of S. persica extracts on human oral Jurkat (T leukemia cells). Extracts from Meswak stick and leaves were tested in different concentrations for their cytotoxic and anti-inflammatory activities on human oral Jurkat T- cells. So treated cells viability with increasing concentrations of S. persica stick extract (0.008-0.2 μg/ml) and leaves extract (0.016-0.5 μg/ml) for 24, 48 or 72 hours was assessed by using the mitochondrial dependent reduction of yellow MTT (3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyl tetrazolium bromide) to purple formazan. Also Enzyme-linked immunosorbent assay (ELISA) was performed on supernatants from treated Jurkat T-cells with phytohemagglutinin (PHA) and both extracts to quantify IL-6, IL-8 pro-inflammatory cytokines. Statistically significant differences were indicated by p

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Background and Objectives: It is important to observe oral health in the high-risk group of pregnant women because of their and their fetal health. The purpose of this study was to identify the predictors of oral health condition among pregnant mothers in Rafsanjan city based on theory of planned behavior in 2016. Materials and Methods: In the present descriptive study, 100 pregnant women in Rafsanjan city were selected by cluster sampling. The data collection tools were a demographic questionnaire, a questionnaire for determining the behavior of oral and dental health and a questionnaire for factors affecting oral and dental health behavior based on the constructs of planned behavior theory. Data were analyzed using Pearson's correlation, one-way variance analysis and multiple linear regression. Results: In multiple linear regression analysis, there was a significant relationship between knowledge factors and behavioral intention and family income and the health behavior score of pregnant women (p<0.05). In total, the constructs of the theory of planned behavior explained 22.7% of the changes in the health behavior score of pregnant women. Conclusion: The results of this study indicated that pregnant women had an undesirable situation in field of health behavior. Therefore, it is recommended that interventions be held based on theory of planned behavior in pregnant women with the aim of improving oral health in health centers.