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SummaryIn order to modulate uterine inflammatory response and evaluate the effect of corticosteroid therapy on fertility, 90 cycles of 45 mares were used for artificial insemination with frozen semen, using three different protocols: G1 -inseminated with frozen semen (800 x 10 6 viable spermatozoa pre-freezing) + 20 mL of seminal plasma; G2 -inseminated with frozen semen (800 x 10 6 viable spermatozoa pre-freezing) + corticosteroid therapy; G3 -inseminated with frozen semen (800 x 10 6 viable spermatozoa pre-freezing) + 20 mL of seminal plasma + corticosteroid therapy. Corticosteroid therapy consisted on one administration of prednisolone acetate (0.1mg/Kg -Predef ® ) when mares presented 35mm follicles and uterine edema, concomitantly with the unique dose of hCG (human chorionic gonadotropin), then repeated each 12 hours until ovulation. On first fertility trial, with normal mares, there was no difference between control and treated groups (p>0.05), using seminal plasma associated with corticosteroid therapy (40 vs. 38%, respectively) or corticosteroid therapy alone (40 vs. 45%, respectively). The second fertility trial, performed with mares with previous history of post-insemination endometritis, demonstrated a significant increase of pregnancy rate when mares were submitted to corticosteroid therapy (0.0 vs. 64.5%, respectively; p<0.05). Corticosteroid therapy was shown to be safe, with no physical or reproductive alterations on treated mares, demonstrating to be an adequate option to those animals with history of post-breeding or post-insemination endometritis. Further clinical research is necessary to confirm these results and contribute to the establishment of preventive therapy for cases of post-insemination endometritis.Keywords: Equine, corticosteroid, seminal plasma, frozen semen, fertility, reproduction Einfluss einer Kortikosteroidtherapie auf die Regulierung der uterinen Entzündungsreaktion bei Stuten nach künstlicher Besamung mit Gefriersperma Um die uterine Entzündungsreaktion zu beeinflussen und den Effekt einer Kortikosteroidtherapie auf die Fertilität zu bewerten, wurden 90 Zyklen von 45 Stuten für die künstliche Besamung mit Gefriersperma nach drei verschiedenen Schemata genutzt: G1 -besamt mit Gefriersperma (800 x 10 6 lebensfähige Spermien, vor Gefrieren) + 20 ml Seminalplasma; G2 -besamt mit Gefriersperma (800 x 10 6 lebensfä-hige Spermien, vor Gefrieren) + Kortikosteroidtherapie; G3 -besamt mit Gefriersperma (800 x 10 6 lebensfähige Spermien, vor Gefrieren) + 20 ml Seminalplasma + Kortikosteroidtherapie. Die Kortikosteroidtherapie der Stuten bestand aus der Gabe von Prednisolonacetat (0,1 mg/kg -Predef ® ) mit dem Auftreten 35 mm großer Follikel und eines intrauterinen Ödems, begleitet von einer einmaligen Gabe hCG (humanes Choriongonadotropin). Die Steroidtherapie wurde bis zur Ovulation alle 12 Stunden wiederholt. Beim ersten Versuch mit gesunden Stuten konnten keine Unterschiede in der Trächtigkeitsrate zwischen der Kontrollgruppe und der behandelten Gruppe (p>0,05) festgestellt werden....

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With the purpose of shedding light on some doubts in veterinary oncology, the present article intends to compare the results of histopathological and immunohistochemical examinations of unspecific round cell neoplasia, to realize immunophenotyping of canine lymphoma cases, to establish the T or B origin of neoplastic cells, and to determine the degree of proliferation and apoptosis of lymphomas by immunohistochemistry. Of 11 animals presenting immunohistochemical diagnosis of lymphoma, five had been diagnosed as Lymphoma by HE staining of histopathological slides and six had been classified as unspecific round cell neoplasia. All cases submitted to immunohistochemical examination were T-cell lymphomas. There was a positive correlation between cell proliferation and apoptosis. The comparison among histopathological and immunohistochemical results obtained in the cases examined in the present study suggested that immunohistochemistry is essential for the differentiation of round cell neoplasia. Keywords: dog, histopathology, immunohistochemistry, round cell neoplasia, lymphoma RESUMO Com o objetivo de sanar algumas dúvidas na área da oncologia veterinária, o presente artigo pretende comparar os resultados dos exames histopatológicos e imuno-histoquímicos de neoplasias de células redondas inespecíficas, realizar imunofenotipagem dos casos

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