Denture stomatitis (DS) is frequently associated with high levels of Candida in saliva and deficient denture hygiene. In order to analyse the incidence of DS and its pre-disposing factors, we evaluated 77 edentulous patients before and 6 months after the placement of new complete dentures. Denture stomatitis was observed in 50.6 and 18.2% of the patients at the first and second evaluation, respectively. Salivary flow, Candida counts in saliva and Candida species were similar in both evaluations. Denture stomatitis and Candida in saliva were more common in females. Our results showed that denture replacement and denture hygiene improvement were useful for DS resolution, particularly types I and II. However, oral and denture hygiene must be continuous, inasmuch as salivary Candida counts remained high and it is considered an important pre-disposing factor for DS.
Epidemiological data from oral squamous cell carcinoma (OSCC) is mostly derived from
North American, European and East Asian populations.ObjectiveThe aim of this study was to report the demographic and clinicopathological
features from OSCC diagnosed in an Oral Pathology service in southeastern Brazil
in an 8-year period.Material and MethodsAll OSCC diagnosed from 2005 to 2012 were reviewed, including histological
analysis of all hematoxylin and eosin stained slides and review of all demographic
and clinical information from the laboratory records.ResultsA total of 346 OSCC was retrieved and males represented 67% of the sample. Mean
age of the patients was 62.3 years-old and females were affected a decade older
than males (p<0.001). Mean time of complaint with the tumors was 10 months and
site distribution showed that the border of the tongue (37%), alveolar
mucosa/gingiva (20%) and floor of mouth/ventral tongue (19%) were the most common
affected sites. Mean size of the tumors was 3.4 cm, with no differences for males
and females (p=0.091) and males reported both tobacco and alcohol consumption more
frequently than females. Histological grade of the tumors revealed that 27%, 40%
and 21% of the tumors were, respectively, classified as well-, moderately- and
poorly-differentiated OSCC, 26 cases (7.5%) were microinvasive OSCC and 17 cases
were OSCC variants. OSCC in males mostly affected the border of tongue, floor of
mouth/ventral tongue and alveolar mucosa/gingival, while they were more frequent
on the border of tongue, alveolar mucosa/gingival and buccal mucosa/buccal sulcus
in females (p=0.004).ConclusionsThe present data reflect the epidemiological characteristics of OSCC diagnosed in
a public Oral Pathology laboratory in southeastern Brazil and have highlighted
several differences in clinicopathological features when comparing male and female
OSCC-affected patients.
The areas that remain untouched by Reciproc instruments used with 2.5% NaOCl irrigation as revealed by micro-CT analysis were usually covered with debris, in the form of pulp tissue remnants, bacteria and dentine chips, especially in the apical root canal.
These findings differ from those observed in other odontogenic lesions, such as ameloblastic fibroma, odontogenic myxoma, odontogenic fibroma, and hyperplastic dental follicles. The term primordial odontogenic tumour is proposed to describe this novel lesion.
To analyze clinical, histological, and immunohistochemical prognostic factors in a large series of patients with mucoepidermoid carcinoma (MEC) treated in a single institution, using univariate and multivariate survival analyses.
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