Prognostic Factors in Head and Neck Mucoepidermoid Carcinoma

Abstract

To analyze clinical, histological, and immunohistochemical prognostic factors in a large series of patients with mucoepidermoid carcinoma (MEC) treated in a single institution, using univariate and multivariate survival analyses.

Cancer of the parotid gland; long-term follow-up. A single centre experience on recurrence and survival

“…As in other studies, gender had no impact on survival [8,12]. In several reviews [8Á10,20], it has been reported that tumour size, malignancy grade and extent of the tumour are major determinants predicting survival, which we also observed.…”

“…Postoperative radiotherapy has been used as standard treatment since the 1970s in our material and is recommended in several recently published studies [8,12,13]. However, the role of radiotherapy has been debated by several authors through the years but there now seems to be agreement that nonradical surgery, inoperable tumour due to tumour extension and more advanced stages require adjuvant radiotherapy.…”

“…Due to the variety of histopathology, it is difficult to achieve a complete survey of the disease. In order to obtain homogenous material, the group most often studied is the largest group, mucoepidermoid cancer [12,15,16].…”

Histopathological Spectrum of Salivary Gland Tumours. A Hospital Based Study.

“…The most common malignant salivary gland tumour is the Mucoepidermoid carcinoma which involves mostly the parotid gland followed by the minor and submandibular gland 9 . Adenoid cystic carcinoma (originally known as cylindroma) is a generally slow growing but highly malignant neoplasm with a remarkable capacity for recurrence.…”

Unicystic variant of low grade mucoepidermoid carcinoma: A rare case report

“…The histopathological grading is used as a prognostic indicator, wherein the low-grade MEC has a better 5 year survival rate with 92-100% compared to high-grade MEC with 0-43% survival rate. [5,6] Here, we report a unique case of unicystic variant of low-grade MEC in an adult patient and further insist to consider this rare entity in the differential diagnosis of cystic lesions of the parotid gland and of the oral cavity.…”