Lipomas of the oral cavity: clinical findings, histological classification and proliferative activity of 46 cases

Fregnani, Eduardo Rodrigues; Pires, Fábio Ramôa; Falzoni, Roberto; Lopes, Márcio Ajudarte; Vargas, Pablo Agustı́n

doi:10.1054/ijom.2002.0317

Cited by 301 publications

(386 citation statements)

References 13 publications

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“…and is characterized by a non-well circumscribed (absence of a fibrous capsule) proliferation of mature adipocytes [1,15]. The lipoadenoma is characterized by both neoplastic tissues: glandular acini/ductus and adipose [21].…”

Section: Discussionmentioning

confidence: 99%

“…The lipoadenoma is characterized by both neoplastic tissues: glandular acini/ductus and adipose [21]. In the present cases, we discarded lipoma due to the absence of atrophic non-neoplastic salivary gland tissue; while lipomatosis was discarded because the presence of the fibrous capsule; and lipoadenoma was discarded due to the absence of neoplastic (glandular or adipocytes) tissue [15]. Another differential diagnosis could include pleomorphic adenoma with lipometaplasia [22].…”

Section: Discussionmentioning

confidence: 99%

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Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze

Huerta

Rivera

Rocha

et al. 2014

Indian J Otolaryngol Head Neck Surg

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Sialolipoma is rare benign neoplasm arise from salivary glands (majors and minors) characterized by neoplastic adipose tissue with scattered non-neoplastic salivary gland acinus. To date 60 cases (including 5 cases reported in the present paper) have been reported in scientific literature. This article presents 5 new cases of sialolipoma affecting minor salivary glands (MiSG) and additionally reviews and analyzes the previously published cases to assess possible demographical differences between sialolipoma from minor and from major salivary glands. Case reports: 5 cases (3 females; 2 males; age means 63.8 years), of sialolipoma from MiSG, are reported. 2 of them were located in buccal mucosa, 1 in upper lip mucosa, 1 in floor of the mouth and 1 in retromolar area. All tumors were composed by neoplastic adipocytes cells interlaced with normal salivary gland acinus cover it by a fibrous tissue capsule. Analyzes of literature showed that MiSG sialolipoma is most frequent in females over 60 years old, therefore and in conclusion this article assess different demographical profile of sialolipoma in respect to their topography.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze

Huerta

Rivera

Rocha

et al. 2014

Indian J Otolaryngol Head Neck Surg

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“…Oral lipomas may occur in various anatomical sites including the major salivary glands, buccal mucosa, lip, tongue, palate, and floor of the mouth. Of these, the buccal mucosa and buccal vestibule are the most common intraoral sites and account for approximately 50 % of all cases [4]. Histologically, lipomas can be classified as classic lipomas or its variants, such as fibrolipomas, spindle lipomas, intramuscular lipomas, angiolipomas, salivary gland lipomas, pleomorphic lipomas, myxoid lipomas, and atypical lipomas [4,16].…”

Section: Introductionmentioning

confidence: 99%

“…We here analyzed the clinicopathological features and proliferative activities of 24 cases of oral lipomas in our department, and compared the results with 603 cases reported in the literature in English [4][5][6][7][8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Lipomas of the Oral Cavity: Clinicopathological and Immunohistochemical Study of 24 Cases and Review of the Literature

Naruse

Yanamoto

Yamada

et al. 2014

Indian J Otolaryngol Head Neck Surg

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Although lipomas are common soft tissue tumors, few cases of lipoma or its variants have been reported in the oral cavity. We here described the clinical, histological, and immunohistochemical features of 24 cases of oral lipoma obtained from medical records at Nagasaki University Hospital between 1977 and 2010, and also retrospectively reviewed 603 cases of oral lipoma reported in the English literatures. The patients examined comprised 11 men and 13 women with a mean age of 59 years, ranging from 31 to 90 years. The main sites involved were the buccal mucosa (n = 9), followed by the tongue (n = 4), lip and retromolar area (n = 3), floor of the mouth (n = 2), and gingiva (n = 1). The mean tumor size was 2.0 cm, ranging from 0.2 to 5 cm. Histological analysis revealed 20 cases of lipoma, 2 cases of fibrolipoma, and one case each of intramuscular lipoma and spindle cell lipoma. Twenty-three cases were treated surgically while one case underwent biopsy and follow-up. Recurrence was not observed in any case. We reviewed the English literatures, and similar results were obtained. In immunohistochemical analysis, PCNA and ki-67 expression indices were higher in intramuscular lipoma cases than in its variants. Especially, it showed that a long time follow-up may be necessary in ki-67 positive cases.

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“…Buccal and tongue mucosa are the most frequent sites, followed by the floor of the mouth, buccal vestibule, palate, lips, and gingiva [7]. Although a male predominance has been reported [4], some authors found an equal gender distribution for oral lipomas [3]. …”

Section: Discussionmentioning

confidence: 99%

Giant intramuscular lipoma of the tongue: a case report and literature review

Colella

Biondi

Caltabiano

et al. 2009

Cases J

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We herein report a rare case of giant intramuscular lipoma of the tongue. A 75-year-old Italian male presented at our department with a large tumor at the tip of the tongue that had been present for over 30 years. Clinical examination revealed a yellowish lesion, measuring 10 cm in maximum diameter, protruding from lingual surface. Histological examination showed an unencapsulated lipomatous tumor composed of mature adipocytes, uniform in size and shape, diffusely infiltrating striated muscle fibers of the tongue. The patient is well with no local recurrence after a 15-month follow-up period.

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Lipomas of the oral cavity: clinical findings, histological classification and proliferative activity of 46 cases

Cited by 301 publications

References 13 publications

Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze

Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze

Lipomas of the Oral Cavity: Clinicopathological and Immunohistochemical Study of 24 Cases and Review of the Literature

Giant intramuscular lipoma of the tongue: a case report and literature review

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