Stage 0 rectal cancer disease is associated with excellent long-term results irrespective of treatment strategy. Surgical resection may not lead to improved outcome in this situation and may be associated with high rates of temporary or definitive stoma construction and unnecessary morbidity and mortality rates.

The purpose of this study was to investigate energy system contributions and energy costs in combat situations. The sample consisted of 10 male taekwondo athletes (age: 21 ± 6 years old; height: 176.2 ± 5.3 cm; body mass: 67.2 ± 8.9 kg) who compete at the national or international level. To estimate the energy contributions, and total energy cost of the fights, athletes performed a simulated competition consisting of three 2 min rounds with a 1 min recovery between each round. The combats were filmed to quantify the actual time spent fighting in each round. The contribution of the aerobic (W(AER)), anaerobic alactic (W(PCR)), and anaerobic lactic [Formula: see text] energy systems was estimated through the measurement of oxygen consumption during the activity, the fast component of excess post-exercise oxygen consumption, and the change in blood lactate concentration in each round, respectively. The mean ratio of high intensity actions to moments of low intensity (steps and pauses) was ~1:7. The W(AER), W(PCR) and W([La(-)]) system contributions were estimated as 120 ± 22 kJ (66 ± 6%), 54 ± 21 kJ (30 ± 6%), 8.5 kJ (4 ± 2%), respectively. Thus, training sessions should be directed mainly to the improvement of the anaerobic alactic system (responsible by the high-intensity actions), and of the aerobic system (responsible by the recovery process between high-intensity actions).

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OBJECTIVE:The aims of this study were to evaluate the safety and efficacy of laparoscopic abdominoperineal resection compared to conventional approach for surgical treatment of patients with distal rectal cancer presenting with incomplete response after chemoradiation.METHOD: Twenty eight patients with distal rectal adenocarcinoma were randomized to undergo surgical treatment by laparoscopic abdominoperineal resection or conventional approach and evaluated prospectively. Thirteen underwent laparoscopic abdominoperineal resection and 15 conventional approach .RESULTS: There was no significant difference (p<0,05) between the two studied groups regarding: gender, age, body mass index, patients with previous abdominal surgeries, intra and post operative complications, need for blood transfusion, hospital stay after surgery, length of resected segment and pathological staging. Mean operation time was 228 minutes for the laparoscopic abdominoperineal resection versus 284 minutes for the conventional approach (p=0.04). Mean anesthesia duration was shorter (p=0.03) for laparoscopic abdominoperineal resection when compared to conventional approach : 304 and 362 minutes, respectively. There was no need for conversion to open approach in this series. After a mean follow-up of 47.2 months and with the exclusion of two patients in the conventional abdominoperineal resection who presented with unsuspected synchronic metastasis during surgery, local recurrence was observed in two patients in the conventional group and in none in the laparoscopic group.CONCLUSIONS: We conclude that laparoscopic abdominoperineal resection is feasible, similar to conventional approach concerning surgery duration, intra operative morbidity, blood requirements and post operative morbidity. Larger number of cases and an extended follow-up are required to adequate evaluation of oncological results for patients undergoing laparoscopic abdominoperineal resection after chemoradiation for radical treatment of distal rectal cancer.

The avermectins represent a group of natural compounds with potent pesticidal activities. Because of their novel mode of action, they represent an important resource for pest control and resistance management. In the Colorado potato beetle, the house fly, and the two-spotted spider mite, resistance to abamectin is usually autosomal, recessive, and polygenic. Although these aspects are beneficial in resistance management, the fact that resistance could be readily selected for suggests that abamectin needs to be used in moderation. Furthermore, several major resistance mechanisms (e.g. excretion, oxidative metabolism, penetration) and minor factors (e.g. altered target site, conjugation, hydrolysis/sequestration) have been implicated in abamectin resistance. Thus, the question is not whether resistance to abamectin will occur but is simply when and how it will occur. To address this problem, we have gathered information on the genetics, biochemical mechanisms, effectiveness of synergists, and cross-resistances to other insecticides from three abamectin-resistant insects. Judicious implementation of this information may prove useful in the resistance management of this natural pesticide.

CONTEXT AND OBJECTIVE: Most bariatric surgical techniques include essentially non-physiological features like narrowing anastomoses or bands, or digestive segment exclusion, especially the duodenum. This potentially causes symptoms or complications. The aim here was to report on the preliminary results from a new surgical technique for treating morbid obesity that takes a physiological and evolutionary approach. DESIGN AND SETTING: Case series description, in Hospital Israelita Albert Einstein and Hospital da Polícia Militar, São Paulo, and Hospital Vicentino, Ponta Grossa, Paraná. METHODS: The technique included vertical (sleeve) gastrectomy, omentectomy and enterectomy that retained three meters of small bowel (initial jejunum and most of the ileum), i.e. the lower limit for normal adults. The operations on 100 patients are described. RESULTS: The mean follow-up was nine months (range: one to 29 months). The mean reductions in body mass index were 4.3, 6.1, 8.1, 10.1 and 10.7 kg/m², respectively at 1, 2, 4, 6 and 12 months. All patients reported early satiety. There was major improvement in comorbidities, especially diabetes. Operative complications occurred in 7% of patients, all of them resolved without sequelae. There was no mortality. CONCLUSIONS: This procedure creates a proportionally reduced gastrointestinal tract, leaving its basic functions unharmed and producing adaptation of the gastric chamber size to hypercaloric diet. It removes the sources of ghrelin, plasminogen activator inhibitor-1 (PAI-1) and resistin production and leads more nutrients to the distal bowel, with desirable metabolic consequences. Patients do not need nutritional support or drug medication. The procedure is straightforward and safe.

The aims of this study were to compare the training load intended by a coach with the training load perceived by the players, over a 45-week professional futsal team season and to compare the variation of session rating of perceived exertion (sRPE) across different periods of the season. Eighteen Brazilian professional futsal players participated in the study. The players' rating of perceived exertion (RPE) and coach's rating of intended exertion (RIE) were collected daily throughout the study. To compare the sRPE variation, the season was divided into 4 periods as follows: preseason (PRE-SEASON), first competitive period (COMP1), intercompetition period (INTER-COMP), and second competitive period (COMP2). Based on the cluster analyses, the training sessions were classified into 3 different intensity zones (low, moderate, and high). In all the season periods and intensity zones, the players' RPEs were lower than the coach's RIE. In the low-intensity zone, the INTER-COMP demonstrated higher sRPE values than did the other periods. In the moderate-intensity zones, the INTER-COMP and COMP2 were similar. Finally, for the high-zone intensity, the PRE-SEASON demonstrated higher values than did the other periods. We concluded that the coach overestimated the training load reported by the players in almost all intensity training zones and season periods. The RPE scale does not seem to be a suitable tool when used by the coach for intended training load. Therefore, technical staff should constantly review the training goals in each season period through daily training load control, always taking into consideration the possibilities and limitations of the RPE method.

The aim of this study was to compare the perceptual and physiological responses and time-to-exhaustion in high intensity interval exercise (HIIE) protocols that are prescribed based on the relative anaerobic speed reserve (ASR) or maximal aerobic speed (MAS) in athletes with different ASR values, as well as the coefficient of variation (CV) of the abovementioned variables. Eleven long-distance runners and ten rugby players were submitted to five experimental sessions on different days; the first and second session were intended for the determination of the anthropometry, MAS and maximal sprint (MSS). In the subsequent sessions, three HIIE 15:15s protocols were performed until exhaustion (110% MAS, Δ25%ASR, and Δ50%ASR) in random order. The anthropometric characteristics and variables obtained from the MAS and MSS tests in the different groups were compared by Student's unpaired t-test. The analysis of mixed models for repeated measures (groups and protocols) was used to compare the speed, delta blood lactate, rating of perceived exertion, and time-to-exhaustion. Rugby players presented higher ASR (13.6 ± 0.9 km h −1 ) compared to long-distance runners (12.6 ± 0.9 km h −1 ) (P = .049). For the HIIE 15:15s protocols, there were no protocol and group interaction effects. However, lower CV values were observed for time-to-exhaustion (a mean reduction of 52%) and delta blood lactate (a mean reduction of 48%) in Δ25%ASR and Δ50%ASR when compared to 110%MAS. Furthermore, the rating of perceived exertion CV was similar in all HIIE 15:15s protocols. The prescription of intensity of HIIE based on the ASR was able to reduce the inter-subject variability of lactate and time-to-exhaustion in rugby players and long-distance runners.