This work presents the investigation of a solvent assisted bonding process developed for the fabrication of closed micro channels made from polymethylmethacrylate (PMMA). The effects of four processing parameters on the deformation and the bond strength of the micro channel have been investigated using the response surface methodology (RSM). High bond strengths (3.5 ± 0.8 MPa) at low deformations (1.6 ± 0.3 %) have been achieved at the center point of the design of experiment.
A design study of a novel passive strain-sensor technology for the in-situ measurement of small strains on implants, bones or fixation systems is presented. The sensing principle is based on hydro-mechanical strain amplification which allows for the abandonment of any electrical circuits. Thus, the sensor can be fabricated applying solely biocompatible or bioresorbable polymeric materials. Finite element simulations are employed to validate the basic sensing principle and to optimize design parameters according to the required target specifications. Remote wireless and passive signal read-out of the sensor signal can be achieved by advanced ultra-sound imaging technologies. I.
This work presents a new passive sensor concept for monitoring the deformation of orthopedic implants. The novel sensing principle of the WIPSS (wireless implantable passive strain sensor) is based on a hydro-mechanical amplification effect. The WIPSS is entirely made from biocompatible PMMA and consists of a microchannel attached to a reservoir, which is filled with an incompressible fluid. As the reservoir is exposed to strain, its volume changes and consequently the fill level inside the microchannel varies. The wireless detection of the microchannel's strain-dependent fill level is based on ultrasound. The WIPSS' sensing principle is proved by finite-element simulations and the reservoir's design is optimized toward maximum volume change, in order to achieve high sensitivity. A fabrication process for WIPSS sensor devices entirely made from PMMA is presented. The obtained measurement results confirmed the sensor's functionality and showed very good agreement with the obtained results of the conducted FE simulations regarding the sensor's sensitivity. A strain resolution of 1.7 ± 0.2 × 10 −5 was achieved. Further, the determination of the cross-sensitivity to temperature and strains applied out of the sensing direction is presented. The response to dynamic inputs (0.1-5 Hz) has been measured and showed decreasing sensor output with increasing frequency. Test structures of the sensor device allow the application of a signal bandwidth up to 1 Hz. Therefore, the proposed sensor concept of the WIPSS presents a promising new sensor system for static in vivo strain monitoring of orthopedic implants. In combination with the developed ultrasound-based read-out method, this new sensor system offers the potential of wireless sensor read-out with medical ultrasound scanners, which are commercially available.
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