There was no statistical difference between the emergency medicine residents using the Alvarado score and the general surgery residents in terms of suspecting the diagnosis of appendicitis.
BECH performed by emergency physicians may serve as an objective, rapid, non-invasive tool in the assessment of patients presenting with dyspnoea in ED.
AMAÇTravmayı takiben acil servise başvuran hastalarda paramediklerce uygulanan travmaya odaklanmış ultrasonografi değerlendirmesinin (PFAST) serbest sıvı saptamadaki doğ-ruluğu araştırıldı.
GEREÇ VE YÖNTEMDört saatlik teorik ve dört saatlik uygulamalı eğitim sonrası, dört paramedik travma hastalarını ileriye dönük inceledi. Altın standardımız ultrasonografi ve karın bilgisayarlı tomografisinin (KBT) resmi radyolog raporlarıydı. PFAST'in duyarlılık, seçicilik, pozitif ve negatif olabilirlik oranları ve tanısal odds oranı hesaplandı ve ki-kare testi ile SPSS 15.0 kullanılarak analiz edildi.
BULGULARYüz yirmi yedi hasta paramedikler tarafından değerlendi-rildi. On dört hastada karında serbest sıvı vardı. Bunlardan 11 tanesi radyoloji raporlarıyla ve KBT ile uyumlu iken (gerçek pozitifler), üç tanesi negatif geldi (yanlış pozitifler). Yüz on üç olguda PFAST serbest sıvı için negatif idi. Bunlardan 111 tanesinde serbest sıvı yokken (gerçek negatifler), iki tanesinde KBT ile tespit edildi (yanlış negatifler). Sırasıyla duyarlılık, seçicilik, pozitif ve negatif olabilirlik oranları ve tanısal odds oranı 84,62, 97,37, 32,15, 0,16 ve 203,50 idi.
SONUÇÇalışmamız, hastane acil servislerinde paramediklerin yük-sek doğruluk oranıyla FAST uygulayabileceklerini göster-mektedir.
Objective To investigate the expression and importance of the nuclear accumulation of p53 in superficial transitional cell carcinoma (TCC) of the bladder and its role as a predictor of response to treatment.
Patients and methods Tumour samples from 30 patients (two women and 28 men, mean age 60.1 years, range 44–75) with pTa/pT1 tumours were assessed immunohistochemically using the Pab1801 monoclonal antibody and standard avidin‐biotin peroxidase staining for p53 protein.
Results Tumours from six patients (20%) showed nuclear accumulation of p53; five of these patients failed intravesical therapy with bacille Calmette‐Guèrin (BCG) and progressed to muscle invasive and/or metastatic disease, in contrast to six of 24 patients with no detectable nuclear oncoprotein.
Conclusions The nuclear accumulation of p53 appears to be a prognostic indicator of tumour unresponsive to intravesical treatment, even with the most potent agent (BCG). Therefore, early radical treatment modalities must be seriously considered in this group of patients.
The objectives of this study were to determine the role of clinical parameters in detecting intracranial injury and to find out whether cranial computed tomography (CT) is routinely needed for mild head injury (MHI) in Turkey. This retrospective study was conducted by reviewing the records of patients with MHI who underwent cranial CT in our emergency department. We carried out multiple logistic regression analysis, and odds ratios with 95% confidence intervals were calculated by using SPSS 15.0. This study included 923 patients. Positive cranial CT findings were determined in 17 patients (1.8%) and six of them (0.6%) underwent surgery. Statistically significant correlations were found among headache, presence of clinical findings of skull fracture, focal neurological deficit and positive cranial CT findings. Although the incidence of the intracranial lesions, especially those requiring surgery, is low in MHI, the liberal use of CT scanning in MHI seems to be justified in countries such as Turkey.
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