Functionality, usability, and pleasure are the three elements that influence consumers decision-making and behavioral intentions. This study attempts to fill in the gap in the web design literature by justifying the Kansei-based engineering technique by embedding emotional cues in Higher Learning website designs. This study aims to test the effectiveness of a Kansei-based website that was designed in accordance with the Kansei-based standards for web design. Using an online Geneva Emotion Wheel survey, the results suggest that the Kansei-based website elicit favorable positive emotion from users
The presence of conventional bank and Islamic bank in Malaysia has created a competition in capturing customer. Customer of Islamic bank maintained their account with the bank if they are satisfied with the product and services offered to them. Other research reveals that the reasons for Muslim to choose Islamic banking are mostly due to religious concern and motives. This study investigates the relationship between religions; influence by family and friend and finally service quality with customers' behavior towards bank selection preferences. Data was collected from 380 customers using selfadministered questionnaires from various Islamic banks in Miri. Results reveal that service quality and preference of choosing Islamic bank in Miri has a strong and positive relationship. Ultimately, friends and family has more impact towards preference in choosing Islamic bank. Recommendation for future study also discussed.
<div class="WordSection1"><p>The mobile applications (apps) development has been gaining popularity for the past few years. Some mobile apps have been failing in its popularity because of the unattractive user interface and bad interaction with the apps. This was proven by previous researchers who have stated that the interaction between a user of mobile application and a graphical user interface could lead to some misunderstandings, errors and frustration from an inability to achieve a goal and could lead to failure of the mobile application. Most of the mobile application developers have been facing proper graphical user interface design recently. There is a noticeable lack of studies and research in the area of mobile application design compared to web application user interface (UI) design. Therefore, this research was done to evaluate the different gender on the mobile shopping application using eye-tracking technology. This research had proposed guidelines based on gender for mobile shopping application. These proposed guidelines can be preferred in the designing process of a mobile shopping application as it could provide a better user interaction and would prevent failure in its popularity by providing fast and user friendly interface.</p></div>
In recent years the emergence of smartphones has changed the definition of mobile phones. It has become an essential part of the peoples' communication and daily life. Mobile apps have become more popular nowadays with the emergence of smartphones. Mobile app is application software designed to run on perspicacious phones and tablet computers. Shopping apps are now the fastest growing apps among mobile apps. Mobile user interface design (UID) is an essential in the mobile apps development process. A poor user interaction in mobile apps could lead to failure of an app. The used of mental model theory could help the mobile apps developers to design a greater user interface (UI). This study discussed on how mental model theory implemented in interface design practices for a mobile shopping app development. Mental model theory using 'Localization' and content analysis method will be used throughout this research study. The expected output of this research is to develop a fast, user-friendly and strong visual hierarchy interface guideline for a UID of mobile shopping apps. According to this study, different gender had a different mental model on the user interface for a mobile shopping app.
Background: Trimethoprim/sulfamethoxazole or SXT, was previously used as a drug of choice for respiratory tract infections due to Haemophilus influenzae. However, its popularity declines due to increasing numbers of SXT-resistant strains. Trimethoprim resistance in H. influenzae is attributed to chromosomal mutations in dhfr genes encoding dihydrofolate reductase (DHFR) while sulfonamide resistance is either due to plasmid-mediated sul2, or insertion in the folP gene which encodes for dihydropteroate synthase (DHPS). To further understand the mechanism of SXTresistance in a collection of H. influenzae strains that were isolated in Malaysia, their dhfr and folP genes were sequenced and compared with similar genes in H. influenzae strain Rd KW20 and other H. influenzae strains.Methods & Materials: Antimicrobial susceptibility test and minimal inhibition concentration (MIC) against co-trimoxazole were performed on 34 strains obtained from 10 hospitals, in nine states of Malaysia. All resistant strains were subjected to PCR targeting for dhfr, folP, sul2 genes and plasmids. The amplified products were sequenced and multiple sequence alignment was performed against the DHFR and DHPS of H. influenzae strains in the Genebank.Results: From the total of 34 strains, nine isolates were resistant to SXT with MIC that ranged from 1 to >32 g/ml. Five of these strains each possessed plasmid which carried sul2 gene. Multiple alignment of the nucleotide sequence of dhfr showed that all the SXT-resistant strains had multiple point mutations resulting in 7% change in the protein sequence. An insert of 15-bp nucleic acid in folP was detected in four SXT-resistant strains which lacked plasmid that leads to four amino acids insertion into the gene. The insert was 100% identical to the insert of H. influenzae strain A12. Strains with intermediate resistance had only point mutations in the dhfr gene with no insert in the folP gene. Conclusion:Two mechanisms of SXT-resistance in H. influenzae were observed in the Malaysian strains. Trimethoprim resistance was mainly due to multiple point mutations, while presence of sul2 or DNA insertion in folP contributed to the sulfonamide resistance. Presence of the insert in folP gene is associated to the increase in the level of resistance.
Aims: Streptococcus pneumoniae is the most common bacterial respiratory pathogen that can lead to invasive diseases such as pneumonia, bacteremia, and meningitis. The interaction of S. pneumoniae with host respiratory epithelial cells is crucial in the colonization of human respiratory tract and involve in the virulence. The aim of the study is to investigate the adherence of S. pneumoniae and the effect of serotypic variation on neuraminidase genes (NanA and NanB) after interaction of A549 human lung epithelial cells with S. pneumoniae serotypes. Methodology and results: Six different serotypes of S. pneumoniae were used (1, 3, 5, 19F, 23F, and 14). A549 human lung epithelial cells were inoculated with pneumococcal strains of different serotype for 3 hours. The number of adherent bacteria was determined by serial dilution followed by spread plate technique on tryptic soy agar supplemented with 5% sheep blood. Bacterial RNA was harvested from the infected A549 cells. The differential expression level of neuraminidases was observed by quantitative real-time PCR (qRT-PCR). Based on bacterial adherence assay, serotype 14 showed highest adherence, meanwhile, serotype 23F showed lowest adherence. This suggests that serotype 14 has a better affinity to adhere to A549 cells as compared to serotype 23F. Higher NanA gene expression was observed in serotype 5, 23F and 19F, while lower expression in serotype 14. In contrast, NanB gene shows low-level expression in serotype 23F and 19F, while higher expression in serotype 14. This postulates that NanA and NanB gene may have different functions in the pathogenesis of S. pneumoniae. Conclusion, significance and impact of study: Our finding on differential expression of neuraminidase gene of S. pneumoniae of various serotypes on A549 cells might give a better understanding of host pathogen interaction between bacteria serotypes and host cell.
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