No abstract

Antioxidants were used to prevent oxidation process in foods which lead to rancidity and browning, DNA oxidation and have many positive physiological effects in human. The concentration and the absorption mechanism of natural antioxidants are important in obtaining the maximum beneficial effect. The sources of antioxidants must be carefully considered to maximize absorption and avoid the toxicity of higher concentration of synthetic groups. A general lack of information about antioxidants indicates by a survey of the general public. An organized effort to educate individuals about foods rich in natural antioxidants and the ability to recognize the major synthetic antioxidants on food labels would be highly beneficial, though more research needs to be done to fully understand their physiological effects.

KEYWORDSFive main flavonoid glycosides were isolated from the ethanolic extract of Diplotaxis harra (Cruciferae), and were identified as quercetin, isorhamnetin 3-rhamnoside, isorhamnetin 3-o-rutinoside, isorhamnetin 3-glucosyl-4`-rhamnoside and isorhamnetin 3-o-β-glucoside. These compounds were identified according to their Rf values, partial and complete acid hydrolysis, UV, 1 H NMR, 13 C NMR and 2D NMR (HSQC, HMBC) spectroscopy. The alcoholic extract of plant was evaluated against some bacterial strains which showed moderate antibacterial activity, while petroleum ether extract doesn't show any activity.

High-purity naringin was isolated from the fruit peels of Citrus maxima and characterized by various spectroscopic methods like UV and NMR. The isolated compound ligand (HL) was used as ligand-metal complexes synthesis after using Ag (I), Y (III) and Ru (III) metals. These ligand-metal complexes were characterized by elemental analysis, FT-IR, UV–VIS, TGA, molar conductance and magnetic properties. Cytotoxic activity of the isolated naringin and its metal complexes were investigated against two human cancer cell lines namely, white breast Adenocarcinoma (MCF7) and Lung carcinoma (A549) using cell viability assay. Transition metal increased the cytotoxic activity of naringin when they were conjugated. LC50 of Ag ligand complex demonstrated strong cytotoxicity against MCF-7 and A549 cell line that was found higher active more than three and four times the strength, respectively when compared to LC50 of Adriamycin. While LC50 of Adriamycin compound was slightly more active only about 30% and twice the strength of the Ru ligand complex against MCF-7 and A549 cell line, respectively.

No abstract

No abstract