Headache is one of the most frequently encountered neurological symptoms during hemodialysis. According to International Classification of Headache criteria dialysis-related headache was defined as the headache occurring during hemodialysis with no specific characteristic. It resolves spontaneously within 72 hours after the hemodialysis session ends. There are few studies in the literature investigating the clinical features of dialysis headache. The pathophysiology of hemodialysis-related headache is not known, but various triggering factors have been identified, including changes in blood pressure, serum sodium and magnesium levels during hemodialysis sessions, caffeine deprivation and stress. The aim of this article is to evaluate and analyze features of headache in patients undergoing hemodialysis.
Background/aim IGF-1 (insulin-like growth factor-1) is an important regulator of bone formation. Its deficiency has been associated with fetal growth disorders and hip dysplasia. The aim of this study was to evaluate whether IGF-1, IGF-BP3 (insulin like growth factor-binding protein 3), and IGF-BP5 levels in the umbilical cord blood can be predictive for early diagnosis of DDH. Materials and methods Umbilical cord blood samples were collected from 860 mothers with pregnancies at high risk for DDH between October 2020 and January 2021. Mothers at 37–42 weeks of gestation, with risk factors for DDH, who delivered healthy infants were included. Blood samples were collected during delivery. Each eligible infant was medically followed up and underwent a hip ultrasound in the postnatal 2nd or 3rd month. Infants diagnosed with DDH were matched with a healthy cohort in terms of sex, birth weight, maternal age, and gestational week, and the IGF-1, IGF-BP3 and IGF-BP5 levels were studied and compared. Results Evaluation was made of 20 infants diagnosed with DDH and 60 healthy infants. Of the total 80 infants, 72.5% were female. The umbilical cord blood levels of IGF-1 and IGF-BP3 were similar in both groups. The IGF-BP5 values were significantly lower in the DDH patient group. Except for DDH diagnosis, the other categorical variables of the study did not appear to influence the levels of any of the IGFs. Conclusion Umbilical blood samples could potentially help diagnose DDH. The levels of IGF-BP5 were shown to be significantly lower in infants with DDH.
Amaç: Yoğun Bakım Ünitesindeki (YBÜ) enfeksiyöz hastalarda mortalite üzerinde etkili olabilecek risk faktörleri olan yaş, eşlik eden hastalıklar, prokalsitonin (PCT), C-reaktif protein (CRP), 25-OH vitamin D düzeyi ve APACHE II skoru ile; bu parametrelerin yoğun bakımda ve hastane sonrası otuz ile doksan günlük mortalite arasındaki ilişkisini değerlendirmeyi amaçladık. Yöntem: Düzce Üniversitesi Tıp Fakültesi İç Hastalıları YBÜ'ye 1 Eylül 2011-30 Ağustos 2012 tarihleri arasında enfeksiyon tanısı ile kabul edilen 52 hasta prospektif olarak değerlendirilmiştir. Bulgular: Sepsis, YBÜ'de mortaliteyi belirgin artırmıştır. Eşlik eden hastalıklardan; hipertansiyon dışındakilerin taburculuk durumuna, 30 ve 90 günlük yaşam süresine ulaşmayla ilişkisi saptanmadı. Yatış laboratuar değerlerinde; CRP ve PCT yüksek, 25-OH vitamin D ise düşük saptanmıştır. YBÜ'den taburculukta; yaş, 25-OH vitamin D, PCT, APACHE II'nin etkili olmadıkları, CRP artışının ölüm riski ile ilişkili olduğu görüldü. APACHE II skoru, otuz günlük yaşamla; yaş ise, otuz ve doksan günlük yaşamla ilişkili bulunmuştur. YBÜ sonrası devredilen serviste yatış süresi uzun olanlarda, hastane sonrası yaşam süresinin yüksek olduğu saptanmıştır Sonuç: Sepsis, YBÜ mortalitesini, sepsisle beraber ileri yaş ta taburculuk sonrası 30 ve 90 günlük mortaliteyi artırabilir. APACHE II skoru, taburculuk sonrası uzun dönem sağkalım tahmininde kullanılabilir. PCT, CRP ve 25-OH vitamin D'nin, YBÜ hastalarının takibi ve prognozunu belirlemede tek başlarına ideal yöntemler olarak kullanılmasının uygun olmadığı düşünülmektedir.Objective: We aimed to investigate the possible risk factors which could effect the mortality of infected patients in Intensive Care Unit (ICU) like age, concomitant diseases, Procalcitonin (PCT), C-reactive protein (CRP), vitamin D levels and APACHE II score. These parameters were also investigated for mortality during hospitalization period and thirty and ninety-day mortality after discharge from hospital. Method: Fifty-two infected patients who were admitted to
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