Pp-079 the Effect of Anemia and Red Cell Transfusions on Mortality in Young and Elderly Intensive Care Patients With Nosocomial Infection

Kutlucan, Leyla; Kutlucan, Ali; Kandiş, Hayati; Titiz, Hafize; Şenocak, Elif; Baştürk, Abdulkadir; Dağlı, Mehmet; Ankaralı, Handan; Geyik, Mehmet Faruk

doi:10.1016/s0145-2126(14)70133-x

Cited by 5 publications

(5 citation statements)

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“…The PLR has been demonstrated to have good predictive value in individuals with cancers [40,41], acute myocardial infarction [42], or stable coronary artery disease [43]. Studies demonstrating a relationship between the PLR and ICU duration of stay [44], and even hospital mortality [45,46], demonstrate how its application in prognostication has expanded to the critically ill population.…”

Section: Discussionmentioning

confidence: 99%

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Alsabani,

Alenezi,

Alotaibi

et al. 2024

Medicina

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Background and Objectives: This study aimed to investigate the role of the pre- and postoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting intensive care unit (ICU) admission and postoperative length of stay (LOS) in bariatric surgery. Materials and Methods: We retrospectively analysed 96 patients who underwent bariatric surgery at our institution. The NLR and PLR were calculated in the pre- and postoperative stages. Changes in pre- and postoperative hematological ratios were compared using the Wilcoxon signed-rank test. The optimal cutoff values and area under the curve (AUC) for each ratio were calculated using receiver operating characteristic (ROC) analysis. Multivariate linear regression analysis was used to assess the relationship between each ratio and the postoperative LOS after adjusting for age, sex, and American Society of Anesthesiologists (ASA) score. Results: The median age of our patients was 35.50 years, and 54.2% were male. The preoperative NLR showed a significant increase from 1.44 to 6.38 postoperatively (p < 0.001). The PLR increased from 107.08 preoperatively to 183.58 postoperatively, p < 0.001). ROC analysis showed that the postoperative NLR was a moderate to high predictor of ICU admission (AUC = 0.700, optimal cutoff point = 5.987). The postoperative PLR had less predictive power for ICU admission (AUC = 0.641, optimal cutoff point = 170.950). Ratios that had a statistically significant relationship with the postoperative LOS were the preoperative NLR (standardized β [95% CI]: 0.296 [0.115–0.598]), postoperative NLR (0.311 [0.034–0.161]), and postoperative PLR (0.236 [0.000–0.005]). Conclusions: The NLR and PLR demonstrated an independent relationship with the postoperative LOS after bariatric surgery and the predictive ability of ICU admission. Both ratios might be useful as simple markers to predict patient outcome after surgery.

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Section: Discussionmentioning

confidence: 99%

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Alsabani,

Alenezi,

Alotaibi

et al. 2024

Medicina

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“…The decrease of Hb in patients may further initiate the immune response, leading to a significant reduction in the number of T lymphocytes, while the significant increase of immunosuppressive factors will lead to decreased immunity which also leads to nosocomial infection [24,25]. Previous studies [23,26] reported that severe reduction of Hb leads to poorer prognosis and increased mortality [22,27,28]. Therefore, to reduce the risk of nosocomial infections in patients undergoing artificial liver therapy, it is necessary to dynamically monitor Hb and actively provide interventions to prevent patients from Hb decrease.…”

Section: Discussionmentioning

confidence: 99%

Risk factors of nosocomial infection in patients underwent artificial liver support system: a retrospective case–control study

Zhang¹,

Qin²,

Liu³

et al. 2023

European Journal of Gastroenterology &Amp; Hepatology

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Background Although nosocomial infection is one of the most discussed problems in patients undergoing artificial liver support system (ALSS) treatment, only few solutions have been proposed so far. This study aimed to explore the risk factors of nosocomial infection in patients treated with ALSS in order to aid in the development of future preventive measures. Methods This retrospective case–control study included patients treated with ALSS at the Department of Infectious Diseases, First Affiliated Hospital of xxx Medical University between January 2016 and December 2021. Results One hundred seventy-four patients were included. There were 57 patients in the nosocomial infection group and 117 patients in the non-nosocomial infection group, of them 127 males (72.99%) and 47 females (27.01%) with an average age of 48.15 ± 14.19 years old. Multivariate logistic regression analysis revealed that total bilirubin [odds ratio (OR) = 1.004; 95% confidence interval (CI), 1.001–1.007; P = 0.020], number of invasive procedures (OR = 2.161; 95% CI, 1.500–3.313; P < 0.001), blood transfusion (OR = 2.526; 95% CI, 1.312–4.864; P = 0.006) were independent risk factors and haemoglobin (Hb) (OR = 0.973; 95% CI, 0.953–0.994; P = 0.011) was a protective factor for nosocomial infection in patients treated with ALSS. Conclusion The total bilirubin, transfusion of blood products and higher number of invasive operations were independent risk factors for nosocomial infection in patients treated with ALSS, while higher Hb was a protective factor.

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“…28,29 Decreased lymphocyte count is the foundation of for using PLR to predict the diagnosis of sepsis in adults. 30 Studies on the use of PLR to predict neonatal sepsis are still rare.…”

Section: Discussionmentioning

confidence: 99%

Platelet-to-lymphocyte ratio in early onset neonatal

Wilar¹,

Rompis²,

Joey

et al. 2023

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Objectives Neonatal sepsis is a major contributor to morbidity and mortality worldwide. Although blood culture is the gold standard of sepsis diagnosis, it often lacks sensitivity and diagnostic speed. Platelet-to-lymphocyte ratio (PLR) is a widely available, effective, simple, and affordable marker that can predict early onset neonatal sepsis (EONS). Objective To assess the correlation between PLR and EONS as well as the diagnostic value of PLR for predicting EONS. Methods This study included all inpatient neonates with suspected early-onset neonatal sepsis at Dr. R. D. Kandou Hospital, Manado, North Sulawesi, Indonesia. Neonates were categorized into sepsis (confirmed by positive blood culture results) and non-sepsis (negative blood culture results) groups. Bivariate analysis, including the chi-square test for categorical data and independent t-test for numerical data, was performed to identify any significant associations between the platelet-to-lymphocyte ratio (PLR) and EONS. The sensitivity, specificity, and area under the receiver operating characteristic (ROC) curve were calculated to determine the optimal PLR cut-off point to predict EONS. Results In this study, we investigated the relationship between PLR and early-onset neonatal sepsis (EONS) in 176 neonates with suspected EONS. Blood cultures confirmed sepsis in 84 neonates (47.7%), with Klebsiella pneumoniae being the most common causative organism. We found a significant positive correlation between PLR and EONS (p<0.001), and a PLR cut-off point of 61.806 was identified to predict EONS with high sensitivity (90.2%) and specificity (85.7%) Conclusion Our study demonstrates a strong positive correlation between PLR and EONS, and a PLR cut-off point of 61.806 can be used as a valuable marker for predicting EONS in neonates with suspected sepsis. These findings could aid in the early identification and treatment of neonates with sepsis, ultimately improving patient outcomes.

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Pp-079 the Effect of Anemia and Red Cell Transfusions on Mortality in Young and Elderly Intensive Care Patients With Nosocomial Infection

Cited by 5 publications

References 0 publications

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Risk factors of nosocomial infection in patients underwent artificial liver support system: a retrospective case–control study

Platelet-to-lymphocyte ratio in early onset neonatal

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