RESUMOIntrodução: O mesocarpo de Orbignya phalerata tem sido usado em estudos experimentais procurando verificar sua ação pró-inflamatória. Objetivo: Analisar comparativamente as alterações histológicas proporcionadas pelo extrato aquoso do Babaçu nas feridas cutâneas. Métodos: Sessenta ratos da linhagem Wistar, adultos, machos, foram utilizados. O procedimento experimental constituiu-se em uma incisão circular de 2cm de diâmetro na pele com punch metálico. Após este procedimento comum a todos, os animais foram distribuídos aleatoriamente em dois grupos contendo 30 animais cada. No grupo controle não foi utilizada a substância pesquisada e sim, solução fisiológica (Cloreto de sódio a 0,9%). No grupo experimento utilizou-se solução aquosa de Orbignya phalerata em uso tópico. Os animais foram acompanhados e mortos em sete, 14 e 21 dias. Foi feita análise histológica comparativa entre os grupos. Resultados: Observou-se diferença significativa a favor da cicatrização do grupo experimento em relação ao grupo controle nos 7º e 14º dias, no que diz respeito à reepitelização. Conclusão: O uso tópico do mesocarpo de Orbignya phalerata (Babassu) contribuiu positivamente para a cicatrização das feridas cutâneas em ratos com a dosagem de 25mg/ml. Descritores: Orbignya phalerata. Cicatrização de Feridas. Pele. Ratos. ABSTRACT Introduction:The mesocarp of Babassu (Orbignya phalerata) has been used in experimental studies trying to check its pro-inflammatory effect. Purpose: To analyse comparatively the histological changes made by the water extract of Babassu in skin surgical wounds. Methods: Sixty Wistar adults male rats were used. The experimental procedure was a circle skin incision of 2 cm in diameter made with a metal punch. After this procedure done in all animals, they were randomized in two groups of 30. In the control group, the phytotherapic agent wasn't used but saline solutin. In the experimental group, the water extract of Orbignya phalerata was used in the cut sites. All animals were followed and killed after seven, 14 and 21 days. Comparative histological analysis was made among the groups. Results: In the microscopic view, a significant reepitelization effect on the healing process of the experimental group in relation to the control group in the 7 th and 14 th days, was recognized. Conclusion: The use of the mesocarp of Orbignya phalerata in skin surgical wounds contributed positively in the healing process in rats. Key words: Orbignya phalerata. Wound Healing. Skin. Rats. IntroduçãoA capacidade de reparação tecidual é fenômeno observado nos seres vivos e de grande importância para sua sobrevivência quando ocorrem lesões acidentais ou cirúrgicas.A cicatrização dos tecidos e órgãos constitui-se em um processo biológico complexo essencial para manter a integridade do organismo, mas que ainda não está totalmente esclarecido.Ao longo dos séculos, procurou-se verificar a ação de substâncias químicas e/ou de procedimentos que pudessem agilizar o processo, quer na ferida limpa, quer na contaminada ou infectada 1 . C...

Background: The health benefits associated with moderate wine consumption, as with ethanol and phenolic compounds, include different mechanisms still little understandable. Aim: Evaluate glycemic and weight variations, and the deposit of triglycerides, cholesterol and liver glycogen with red wine consumption. Methods: 60 ApoE knockout mice were divided into three groups of 20: Wine Group (WG), Ethanol Group (EG) and Water Group (WAG). They received daily: WG 50 ml of wine and 50 ml water; EG 6 ml ethanol and WAG 94 ml of water. All groups were followed for four months. The food intake was monitored daily, in the period from eight to ten hours and held every five days. The measurement of water intake was also made every five days. The weighing of the animals took place every ten days. Results: The WG had higher weight increase as compared to the other groups. The concentration of hepatic triglyceride was higher in WG (57%) and the EG group was lower (31.6%, p<0.01) than the control. The concentration of cholesterol was lower in the WG (23.6%), as well as EG (24.5%, p<0.05). The concentration of glycogen was higher in WG (16%) and fasting blood glucose was higher in EG compared to the other groups but not both demonstrated a statistically significant difference. Conclusion: The WG increased triglyceride and WAG decreased cholesterol. The triglyceride may be increased due to the high caloric value of wine or some unknown property that led to significant increase in subcutaneous andretroperitoneal fat in mice.

OBJETIVO: Avaliar a espirometria no pré e pós-operatório de doentes com sequela de tuberculose, submetidos à lobectomia. MÉTODOS: Foram selecionados 20 doentes, com idade entre 15 e 56 anos, de ambos os sexos, com história pregressa de tratamento de tuberculose, apresentando infecção de repetição ou hemoptises. Foram submetidos à lobectomia pulmonar. O tempo de tratamento da tuberculose foi seis meses e o aparecimento dos sintomas entre um e 32 anos. Foram avaliadas a capacidade vital (CV), a capacidade vital forçada (CVF), o volume expiratório forçado (VEF1), o VEF1/CVF, o fluxo expiratório forçado (FEF) e o pico de fluxo expiratório (PFE) após o primeiro, terceiro e sexto meses em relação ao pré-operatório. O nível de significância (á) aplicado em todos os testes foi 5%, ou seja, considerou-se significativo quando p<0,05. RESULTADOS: As Médias encontradas foram as seguintes: Capacidade Vital (CV) Pré-operatória-2,83 ; 1º PO 2,12; 3º PO 2,31; 6º PO 2,43. Capacidade Vital Forçada (CVF) Pré-operatória- 2,97; 1º PO 2,21; 3º PO 2,35; 6º PO 2,53. Volume Expiratório no 1º Segundo (VEF1) Pré-operatório 2,23; 1º PO 1,75; 3º PO 1,81; 6º PO 1,97. Houve diminuição acentuada das funções respiratórias no primeiro mês de pós-operatório, porém houve melhora dos parâmetros a partir do terceiro mês, com progressivo aumento até o sexto mês de pós-operatório. CONCLUSÃO: Não houve recuperação dos parâmetros espirométricos, comparados aos do pré operatório, após seis meses de pós-operatório nos pacientes com sequela de tuberculose submetidos à lobectomia.

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Introduction: Pentalogy of Cantrell is a rare disorder described by Cantrell in 1958 and characterized by heart anomalies, involving defects of the diaphragm, abdominal wall, supraumbilical region and pericardium. Methods: We report a case of the disease that presented with agenesis of the sternum and partial absence of costal cartilage, treated by a multidisciplinary team. Results: The patient underwent median sternotomy. An enlarged heart, compromising the pulmonary trunk and the right ventricle, and a left superior vena cava were identified. The right atrium was opened and an interventricular communication of around 10 mm in diameter was seen through the tricuspid valve. Following the repair of the heart defects, chondroplasty and placement of biological mesh (Bioway of Gore) were performed. Conclusion: A Successful surgical treatment for Cantrell Syndrome includes correction of the cardiac malformation, a good repair of thoracoabdominal wall.

Pulmonary hyalinizing granuloma (PHG) is a rare nodular disease of unknown etiology. PHG can present with solitary or bilateral lung nodules and be asymptomatic or present with fever, cough, dyspnea, chest pain and hemoptysis.

Introduction: Traumatic right diaphragmatic hernia is an extremely rare entity, given the protection afforded by the liver. Clinical Case: A 51-year-old women who suffered a road-traffic accident presented with a heavy sensation and several episodes of moderate pain in the left hemithorax. Physical and radiological exams revealed a traumatic right hernia. Discussion: The diagnosis of hernia should be established as quickly as possible to reduce morbidity and mortality. Treatment of the injury is always surgical and outcome is invariably positive. Conclusion: The diagnosis of diaphragmatic hernia should always be considered in patients suffering road-traffic accidents to allow early diagnosis and successful treatment.

Thymomas are rare neoplasms of mediastinum. We present two cases of large asymptomatic thymomas exceeding the mediastinal space and surgically managed in an university hospital. The larger tumor weighted 950g and the other 500g (Rev. Col. Bras. Cir. 2005; 32(5): 283-284).