Fetal growth defect is classified into intrauterine growth restriction (IUGR) and small-forgestational-age (SGA) fetus based on the estimated fetal weight percentile and Doppler hemodynamic parameters. IUGR pathophysiology and etiology are complex and diverse, highlighting placental insufficiency as a paradigm, which explains its association with other entities of great clinical importance such as preeclampsia. The poor long-and shortterm perinatal and postnatal results associated with this context make it necessary to establish an early diagnosis and a therapeutic strategy, which can be challenging due to the compromise between the threat of intrauterine permanence and the prematurity problem. Consequently, a systematic and protocolized diagnostic-therapeutic management, based on scientific evidence, is necessary to determine whether obstetric intervention through a preterm delivery is advisable to improve the perinatal outcomes of these patients.
and abnormal S/D ratio group(n = 11). All cases were delivered at 37 + 0-41 + 6 weeks of gestational age from January 2001 to December 2008 at Ajou University Medical Center. The criteria for S/D ratio of umbilical artery was 3.0 and the neonatal weight < 10percentile compared to gestational age was used for definition of IUGR. Gas analysis and blood tests, including nRBC count in umbilical artery, were done during delivery. Results: The abnormal S/D ratio group showed significantly higher numbers of nRBC compared to the other groups (2.25 vs 4.67 vs 8.91/WBC100, p < 0.05). Also there was a significant decrease of neonatal weight in the abnormal S/D ratio group compared to the other groups (2130gm vs 2420gm vs 3211gm, p < 0.005). Conclusions: The number of nRBC of the umbilical artery showed an increase in the group of abnormal S/D ratio and associated with decreased neonatal weight.
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