Psoriasis is a common systemic inflammatory disease with multiple known comorbidities. We review the literature focusing on the psychological comorbidities that have been reported. We discuss the impact of psoriasis on stress and sleep disorders in addition to depression. Alcohol abuse and nicotine addiction are prevalent in this population, as are psychological problems in children and teenagers who develop psoriasis early in life. We summarize the proposed pathophysiology and known treatments for these comorbidities.
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