Psoriasis and Psychological Comorbidities

Prussick, Lisa; Jimenez, E. Romo; Nussbaum, Dillon; Prussick, Ronald

doi:10.1177/247553031600100206

Cited by 6 publications

(3 citation statements)

References 47 publications

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“…The higher prevalence of alcoholic CM in patients with psoriasis can be attributed to the higher prevalence of alcoholism in patients with psoriasis (31% vs 19%, Table 1 ). Although not statistically significant, the association between alcoholic CM and psoriasis is noticeably observed at 0.941% in our study which could be attributed to the psychosocial aspects and consequences of this debilitating autoimmune disease [ 24 , 25 ]. As viral cardiomyopathy is the only type that has been noticed to be associated with psoriasis in our current study, several explanations could justify this higher incidence.…”

Section: Discussionmentioning

confidence: 55%

Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

Alshami

Alfraji

Douedi

et al. 2021

BMC Cardiovasc Disord

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Background Psoriasis is a chronic inflammatory skin condition commonly associated with psoriatic arthritis, malignancy, diabetes, inflammatory bowel disease, and cardiovascular disease. Several reports and studies have reported an association between psoriasis and non-ischemic dilated cardiomyopathy (NIDCM). We aim to study the relationship between psoriasis and non-ischemic dilated cardiomyopathy in a large population-based study. Methods We utilized the Healthcare Cost and Utilization Project National Inpatient Sample 2017 database, which represents a 20% sample of all payer hospitalizations in the United States. We investigated hospitalizations for patients aged 18 years old or older with diagnoses of any type of psoriasis and non-ischemic dilated cardiomyopathy. Psoriasis, cardiomyopathy, and other comorbidities were identified through their international classification of diseases, 10th revision codes recorded in the discharge record for each hospitalization. Results Of a total of 6,084,184 all-cause admissions, 0.5% were admissions for patients with psoriasis (n = 32,807). Of the patients with and without psoriasis who had non-ischemic dilated cardiomyopathy, after adjusting for age, sex, race, diabetes mellitus, hypertension, alcohol abuse, cocaine abuse, arrhythmias, and obesity in a multivariate analysis, the presence of psoriasis was not significantly associated with non-ischemic dilated cardiomyopathy. Conclusion Psoriasis is a chronic autoimmune disorder which carries a higher cardiovascular events and more prevalent traditional atherosclerotic risk factors in comparison to the general population. However, association with non-ischemic cardiomyopathy or NIDCM in particular has not been studied sufficiently. Our study, being one of the first larger studies to assess this correlation, indicated no relationship between psoriasis and non-ischemic dilated cardiomyopathy.

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Section: Discussionmentioning

confidence: 55%

Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

Alshami

Alfraji

Douedi

et al. 2021

BMC Cardiovasc Disord

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“…Focussing on the psychological impact of skin conditions has long been seen as necessary 28 if patient treatments are to be optimized, with calls growing for interventions to be more psychologically informed. 29 , 30 However, the All‐Party Parliamentary Group on Skin 31 reported that 98% of people surveyed felt psychologically negatively impacted by their skin condition, but only 18% had received support. Despite the increasing interest in psychosocial aspects of autoimmune conditions, there is a scarcity of research examining anger associated with psoriasis.…”

Section: Introductionmentioning

confidence: 99%

Understanding the experiences of anger in the onset and progression of psoriasis: A thematic analysis

Hughes

Hunter

2022

Skin Health and Disease

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Psoriasis is a chronic inflammatory skin condition, which can be affected by stress. Living with psoriasis can trigger negative emotions, which may influence quality of life. The present study explored the lived experiences of people with psoriasis with attention to the potential role of anger in the onset and progression of the chronic skin condition. Semi-structured qualitative interviews were conducted with 12 participants (n = 5 females, n = 7 males) recruited from an advert on a patient charity social media platform. Data were transcribed and analysed using thematic analysis. Four key themes were identified: (1) anger at the self and others, (2) the impact of anger on psoriasis: angry skin, (3) shared experiences of distress and (4) moving past anger to affirmation. Findings suggest that anger can have a perceived impact on psoriasis through contributing to sensory symptoms and unhelpful coping cycles, and points to a need for enhanced treatment with more psychological support. The findings also highlight the continued stigma which exists for those living with visible skin conditions and how this may sustain anger for those individuals. Future research could usefully focus on developing targeted psychosocial interventions to promote healthy emotional coping.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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“…Psoriatic arthritis (PsA) is known as chronic inflammatory disease affecting skin, joints and presents high genetic polimorfism 1 . Prevalence of PsA is 2-3% population worldwide and correlates with several comorbidities 2,3 . This condition has been described as mediated by T helper cell type 17 (Th17) immune response characterized for increased levels of several proinflammatory cytokines such as interleukin (IL)-1, IL-6, IL-8, IL-17, tumor necrose factor-α (TNF-α) and a rich leukocyte recruitment mainly neutrophils into joints and skin lesions 4 .…”

Section: Introductionmentioning

confidence: 99%

Management of youth psoriatic arthritis with etanercept: a case report

Bezerra-Santos

Palitot

Brito

et al. 2018

MRAJ

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Psoriatic arthritis (PsA) is an immune-mediated inflammatory disease of the skin and joints still poorly understood in pediatric patients. It has been reported a case report of PsA in a male infant patient in Paraiba state, Northeast Brazil. The goal of this study was describing a rare case of juvenile PsA and its management upon using classical and biological treatment based on the drug etanercept. The patient was diagnosed with scales on the scalp, knees and other parts of the body and joint inflammation besides social behavior deficit since he was aged 5. Classical therapy to PsA including acitretin and topical glucocorticoids did not ameliorate the illness symptoms. Then, the patient received the anti-TNF-α drug etanercept used to treat moderate to severe psoriasis and juvenile rheumatoid arthritis. Before the week 16 of the treatment was observed a strong remission of the symptoms which is related to the inhibition of the inflammatory response into skin and joints. Besides no side effects was observed during etanercept administration.

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Psoriasis and Psychological Comorbidities

Cited by 6 publications

References 47 publications

Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

Understanding the experiences of anger in the onset and progression of psoriasis: A thematic analysis

Management of youth psoriatic arthritis with etanercept: a case report

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