The discussion of factors predisposing to oral yeast infections is very important, and we can ask: what is primary and what is secondary? Without predisposing factors it is difficult to have oral yeast infection, and a yeast infection may also be the first sign of a developing basic illness. As long as the predisposing factors cannot be eliminated, recurrences of oral yeast infections are to be expected. We can say that local and systemic factors permit this micro-organism to cause disease and that it is extremely rare to find a case of oral candidosis in which one or more of these factors cannot be identified. There are many kinds of lists in the textbooks and some review articles in the literature, but more research is needed for better understanding of factors predisposing to oral yeast infections.

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A double-blind, randomized trial was carried out in patients suffering from pain after removal of an impacted lower wisdom tooth. The analgesic effects of a codeine preparation (Staralgin), a dextropropoxyphene preparation (Doleron novum), and paracetamol were compared in a multiple-dose study of 94 patients. The assessments of pain were made hourly on a visual analog scale, and the evaluation was carried out according to a method which takes into account both duration of effect and number of tablets taken. The most pronounced pain reduction and the highest proportion of pain-free patients were reached with the dextropropoxyphene preparation. The reported side effects were few and equally distributed among the treatment groups. The method of evaluation is discussed, and it was noted that the pain score at tablet intake might be of significant importance in comparison of analgesics.