In this article we propose a novel label-free chemical/biochemical sensing device based on a waveguide resonator with an integrated microfluidic channel. This device is intended for the characterisation and detection of cells and various chemical substances from within a variety of micro-litre test samples. This paper outlines the design of the prototype device and describes the fabrication of the microfluidic network and microwave resonator. Initial testing of the prototype at Xband is examined with promising results. Finally, we propose a Low Temperature Co-fired Ceramic (LTCC) integration scheme for the miniaturization of the device for use in the THz regime.
A two dimensional perturbed Frequency Selective Surface (FSS) with enhanced near-fields has been used for microwave sensing applications. The perturbation causes the scattering by the perturbed array, within a frequency range to be dominated by an odd mode which gives rise to a sharp resonance with a seven-fold near field enhancement compared to the unperturbed array. The spectral shift of the odd resonance is studied for small variations of the electric permittivity of the supporting substrates. The aperture FSS is shown theoretically to increase the sensor sensitivity. The FSS is integrated with a microfluidic channel inside a waveguide simulator to ease the fabrication process and the performance of the ensemble is investigated for different samples inside the channel.
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