Label-free chemical/biochemical sensing device based on an integrated microfluidic channel within a waveguide resonator

Abstract

In this article we propose a novel label-free chemical/biochemical sensing device based on a waveguide resonator with an integrated microfluidic channel. This device is intended for the characterisation and detection of cells and various chemical substances from within a variety of micro-litre test samples. This paper outlines the design of the prototype device and describes the fabrication of the microfluidic network and microwave resonator. Initial testing of the prototype at Xband is examined with promising results. Finally, we propose a Low Temperature Co-fired Ceramic (LTCC) integration scheme for the miniaturization of the device for use in the THz regime.

Analysis of Microfluidic Pipes in a W-band Waveguide for Determining Complex Permittivity

“…In literature, for waveguide based methods, most of the work focuses primarily on resonant techniques, such as ridgegap waveguides, whispering gallery modes, photonic crystal resonators, filter based waveguide methods, and waveguide slot antenna based sensors [4,5,6,7,8]. These methods are all inherently narrowband and hence limit extraction of permittivity to a single frequency.…”