The Lossen rearrangement is a classic process for transforming activated hydroxamic acids into isocyanate under basic or thermal conditions. In the current report we disclosed a consecutive Lossen rearrangement/transamidation reaction in which unactivated hydroxamic acids were converted into N-substituted formamides in a one-pot manner under catalyst- and additive-free conditions. One feature of this novel transformation is that the formamide plays triple roles in the reaction by acting as a readily available solvent, a promoter for additive-free Lossen rearrangement, and a source of the formyl group in the final products. Acyl groups other than formyl could also be introduced into the product when changing the solvent to other low molecular weight aliphatic amide derivatives. The solvent-promoted Lossen rearrangement was better understood by DFT calculations, and the intermediacy of isocyanate and amine was supported well by experiments, in which the desired products were obtained in excellent yields under similar conditions. Not only monosubstituted formamides were synthesized from hydroxamic acids, but also N,N-disubstituted formamides were obtained when secondary amines were used as precursors.

In order to explore the development of research of science teacher(RST), 904 articles from the Web of Science (WoS) core set based on bibliometric methods through R software were analyzed in this research. Specifically, it examined the cooccurrence relations of countries/regions, major journals, most cited references, and hot keywords from the macroscopic, mesoscopic and microscopic level of RST. The results showed that the core strength of RST is mainly from traditional industrialized countries such as the United States, Australia, and Britain. And some top journals in science education (such as Journal of Research in Science Teaching, Science Education) has to pay more attention on RST, it may also appeal to lots of top journals in general teacher education (such as Journal of Teacher Education, Teaching and Teaher Education). The research on science teachers was guided by several educational theories about teacher research, such as the teacher epistemological belief, reflective practice, and PCK. Moreover, theories in science education such as scientific literacy, scientific conceptual change also becomes the theoretical basis for science teachers' teaching practice and scientific inquiry instructing. The knowledge, key competences, dispositions, and professional development of science teacher are the main keywords and hot topics in the field of RST.

Multiple pathways for C–H cleavage was uncovered in cationic Cp*Rh(iii)-catalyzed C–H functionalization with different heteroatom-containing species as possible proton acceptors.

Key indicatorsSingle-crystal X-ray study T = 298 K Mean (C-C) = 0.005 Å R factor = 0.066 wR factor = 0.186 Data-to-parameter ratio = 13.3For details of how these key indicators were automatically derived from the article, see

The paper elaborates the features and superiority of applying multimedia technology to chemistry experiment instruction in details, and introduces the practical application of multimedia technology in demonstration experiment. The application of multimedia technology in chemistry experimental instruction has its own features, namely enjoyment, great information capacity, sharing network, easy operation and flexibility. The paper concludes the superiority of applying multimedia technology to the chemistry experiment instruction from nine perspectives. Meanwhile, the paper elaborates its disadvantages. Simulated experiments cannot take place of real experiments. The relationship among teachers, students and multimedia needs to be dealt with properly, and the multimedia courseware should be scientific. Prospective forecast of multimedia technology in chemistry experimental instruction is also demonstrated.