Nevus lipomatosus superficialis (NLS) is an uncommon hamartomatous lesion of the skin characterized by the presence of clusters of mature fat cells among the collagen bundles of the dermis. Usually, the number of adnexal structures is reduced in NLS as compared to the normal adjacent skin, but their morphology is not altered. Nevertheless, in some instances, associated pilar abnormalities have been reported. We here report 2 cases of NLS with disorganized pilosebaceous units. The follicular structures were dilated and showed infundibular type keratinization and there were numerous mature sebaceous lobules radiating from them resembling the histology of a folliculosebaceous cystic hamartoma (FSCH) or a sebaceous trichofolliculoma. Only 2 cases of NLS with FSCH have been previously reported. Our cases represent examples of a very rare hamartomatous cutaneous lesion composed of mesenchymal and epithelial components.
We report the case of a 35-year-old woman with deep-red asymptomatic macules on the
plantar and dorsal skin of the right great toe. Histopathologic fi ndings were
compatible with Angioma serpiginosum. Immunohistochemical stains for estrogens and
progesterone receptors were negative. Dermoscopy showed an erythematous parallel
ridge pattern with double rows of irregular dots and globules. We report an unusual
case of angioma serpiginosum with acral volar skin involvement. The dermoscopic
features described may aid in the diagnosis of AS in this specifi c skin area. Acral
volar skin involvement must be included in the clinical spectrum of Angioma
serpiginosum and in the differential diagnosis of acral vascular lesions.
A female patient presented at birth with a painless bulky mass located on the vertex. She was a term baby with a normal antenatal history. The child was otherwise healthy. Physical examination showed a single, well-defined purplish-red tumoral lesion with arborizing telangiectasias over the surface (Fig. 1). It was located on the parieto-occipital region, 5 · 3 cm in size and was firm on palpation, with no apparent underlaying bony defect. Radiologic investigations, including transfontanellar cranial ultrasonography and cranial magnetic resonance imaging, revealed no malformations of the central nervous system and demonstrated a minimally enhancing subcutaneous soft-tissue mass with a focal destructive remodeling of the outer table (Fig. 2). Abdominal ultrasonography showed no abnormalities.A biopsy was performed, and histopathological examination of hematoxylin-eosin and Masson's trichrome stained sections showed a well-circumscribed mass. Higher power views are seen in Figs. 3 and 4.
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