Objective The aim of the study was to compare the effects of single intra-articular platelet-rich plasma (PRP) and corticosteroid (CS) injections in patients with adhesive capsulitis of the shoulder. Design Patients aged 18–70 yrs of either sex, diagnosed with adhesive capsulitis of shoulder, with less than 6-mo duration, were included. In intra-articular corticosteroid (IA-CS, control) group, 30 patients received a single injection (4 ml) of IA-CS and in IA-PRP (test) group, 30 patients received single IA-PRP injection (4 ml) into the glenohumeral joint under ultrasound guidance. All patients were prospectively followed for 12 wks. Results Twenty-eight patients in IA-PRP group and 27 in IA-CS group finished the entire 12-wk study period. At 12 wks, decrements in visual analog scale and total shoulder pain and disability index scores, in IA-PRP group, were 58.4 and 55.1, compared with 48.7 and 45.8 in IA-CS group. In range of movement, IA-PRP group showed significant improvement in passive abduction (−50.4 vs. −39.4), internal (−36.8 vs. −25.8), and external rotations (−35.4 vs. −25.9) compared with IA-CS group, respectively. No major complications were observed in any patients. Conclusions At 12-wk follow-up, a single dose of IA-PRP injection was found to be more effective than an IA-CS injection, in terms of improving pain, disability, and shoulder range of movement in patients with adhesive capsulitis of the shoulder.

Background: Transfusion transmitted infections (TTIs) involves several adverse consequences. Studies have shown that ABO blood groups have some association with various infectious and non-infectious diseases. Few blood groups even can act as a receptor and ligand for infectious agents. The objective of the study was to find out any significant association of TTIs with various ABO and Rh D blood group system.Methods: This retrospective study was conducted from July 2016 to October 2018. Blood donors’ blood was tested for ABO and Rh D grouping and five mandatory TTI markers as per Drugs and Cosmetics Act. Chi-square test was performed to look for any association of TTIs with ABO and Rh D blood group.Results: 10,510 healthy donors were screened for TTI and 199 (1.89%) were positive for various TTIs. Hepatitis B had maximum prevalence (102 cases, 0.97%) followed by Hepatitis C (44 cases, 0.41%) and HIV (37 cases, 0.35%). Maximum TTI seroreactive donors were found among ‘B’ blood group (2.21%, 77 cases) followed group ‘A’ donors (2.16%, 53 cases), ‘O’ donors (1.57%, 60 cases) and ‘AB’ donors (1.17%, 9 cases), respectively. However, the risk of association of TTI was not statistically significant with ABO and Rh D blood group.Conclusions: Although no significant association was observed between ABO and Rh D blood groups with TTIs, Hepatitis B was found to be most common infection in blood donors. This high prevalence points towards critical need of comprehensive public health approach to achieve elimination of TTI.

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