The seeds of Tectona grandis Linn. are traditionally acclaimed as hair tonic in the Indian system of medicine. Studies were therefore undertaken in order to evaluate petroleum ether extract of T. grandis seeds for its effect on hair growth in albino mice. The 5% and 10% extracts incorporated into simple ointment base were applied topically on shaved denuded skin of albino mice. The time required for initiation of hair growth as well as completion of hair growth cycle was recorded. Minoxidil 2% solution was applied topically and served as positive control. The result of treatment with minoxidil 2% is 49% hair in anagenic phase. Hair growth initiation time was significantly reduced to half on treatment with the extracts compared to control animals. The treatment was successful in bringing a greater number of hair follicles (64% and 51%) in anagenic phase than standard minoxidil (49%). The results of treatment with 5% and 10% petroleum ether extracts were comparable to the positive control minoxidil.

Background: Iron deficiency anemia is common problem in children, though the oral iron therapy is the main stay of treatment, but most of children not responding to it due to non-compliance. So the parental iron therapy is the treatment of choice for it. Methods: Fifty children between the age group of 1-17 years of age were selected for this study diagnosed as iron deficiency anemia. Iron sucrose given by IV according to their weight and age. CBC performed before starting of study and after receiving Iron sucrose intravenously i.e. after 4, 10 and 30 days of iron sucrose. Results: Among the red cell indices, mean corpuscular volume and mean corpuscular haemoglobin in this study we got mark improvement in both the parameters along with improvement in PCV and finally increase in haemoglobin level. All the parameters having P value highly significant i.e. <0.001 along with minimal side effects. Conclusions: Iron sucrose can be safely used in children.

Tectona Grandis Linn.(saag - tick wood), an indigenous medicinal plant, has a folk reputation among the Indian herbs as a hypoglycemic agent. The present study was carried out to evaluate the anti-hyperglycemic effect of T. grandis Linn. bark extract in control and alloxan-diabetic rats. Oral administration of the bark suspension of T. grandis (2.5 and 5 g/kg body wt.) for 30 days resulted in a significant reduction in blood glucose (from 250 ± 6.5 to 50 ± 2.5 mg/dL). Thus, the present study clearly shows that the T. grandis Linn. bark extract exerts anti-hyperglycemic activity.

Background: Cough is protective reflex caused by obstruction or irritation of airway. Many medication available for the treatment of dry cough. But it causes sedation and drowsiness in children. Considering the adverse effects produce by the medication, we consider this study as the ginger and honey is used in Indian family, and in Ayurveda ginger and honey is used for treatment of dry and productive cough.Methods: We include the patients who attended the pediatric OPD complaining dry cough. We design the questionnaire and for the measuring the severity of dry cough. We divide the patient into four groups received standard treatment and ginger and honey mixture. We compared the end result with standard treatment statistically by using unpaired student “t” test was used along with two-way analysis of variance (ANOVA) test.Results: We include 100 patient in this study. We got amazing result of this study ginger and honey required less time for recovery and also sedation and drowsiness not occurred in the ginger and honey group as compared to dextromethorphan (p value ˂0.005).Conclusions: After seeing above encouraging result, and along with advantage of natural product with no adverse we can advise the honey and ginger therapy for treatment of dry cough.

Background: Neonatal sepsis is one of the major cause of mortality and morbidity Globally, objective of this prospective study was to evaluate the microorganisms profile involved in neonatal septicemia and their antibiotic susceptibility. Methods: This prospective study conducted in neonate admitted to Mahatma Gandhi Mission Medical College and Hospital Aurangabad Maharashtra in NICU, from June 2021 to May 31, 2022. Data was analysed by percentages of each antibiotic used. And which organism was responsible for neonatal sepsis. Results: In this study we have found that high bacterial prevalence of Klebsiella at 36%, Enterococci at 23.5 and staph aureus at 19.8% in neonatal sepsis. While the antibiotics most used was Piperacillin and tazobactam, meropenam, colistin, cefotaxime, amikacin. In our setting we found that bacteria are still sensitive to third generation cephlosporings. Conclusions: From our study we can conclude that, in our tertiary care hospital Klebsiella is major cause of neonatal sepsis, along with-it sensitivity with effectiveness of cephalosporin.