2010
DOI: 10.4103/0974-7788.76783
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Effect of Tectona grandis Linn. seeds on hair growth activity of albino mice

Abstract: The seeds of Tectona grandis Linn. are traditionally acclaimed as hair tonic in the Indian system of medicine. Studies were therefore undertaken in order to evaluate petroleum ether extract of T. grandis seeds for its effect on hair growth in albino mice. The 5% and 10% extracts incorporated into simple ointment base were applied topically on shaved denuded skin of albino mice. The time required for initiation of hair growth as well as completion of hair growth cycle was recorded. Minoxidil 2% solution was app… Show more

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Cited by 23 publications
(19 citation statements)
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“…It is also used for the treatment of anemia and shows anti-hemolytic anemia activity (Diallo et al 2008). Its seeds are acclaimed to be hair tonic, which is reported to increase the number of hair follicles in the anagenic phase (Jaybhaye et al 2010). Its leaves, bark, and wood show antioxidant properties, with wood showing the highest (98.6%) inhibition against DPPH (Krishna and Jayakumaran 2010).…”
Section: Introductionmentioning
confidence: 99%
“…It is also used for the treatment of anemia and shows anti-hemolytic anemia activity (Diallo et al 2008). Its seeds are acclaimed to be hair tonic, which is reported to increase the number of hair follicles in the anagenic phase (Jaybhaye et al 2010). Its leaves, bark, and wood show antioxidant properties, with wood showing the highest (98.6%) inhibition against DPPH (Krishna and Jayakumaran 2010).…”
Section: Introductionmentioning
confidence: 99%
“…This plant is verified to have hair growth activity [188], cytotoxic activity [189], anti-hemolytic anemia activity [190], hypoglycemic activity [191], anti-inflammatory activity [192], diuretic activity [193], and gastroprotective activity [194].…”
Section: Scientific Evidencesmentioning
confidence: 99%
“…The wood is used to relax and sedate the gravid uterus, heal headache and burning pains, cure liver problems, and even dysentery. T. grandis has been investigated in some studies for its anti-inflammatory and wound healing effects and is used as a topical treatment for burn wounds [113,114]. Jaybhaye et al investigated the effect of petroleum ether extract of T. grandis Linn.…”
Section: Tectona Grandis Linnmentioning
confidence: 99%
“…According to this study, topical application of the petroleum ether extract of T. grandis induced hair growth initiation and was superior to standard therapy with minoxidil 2% solution. The combination of the petroleum ether extract (5%) with 2% minoxidil has the strongest effect on hair growth initiation [113].…”
Section: Tectona Grandis Linnmentioning
confidence: 99%