Single photon emission computed tomography (SPECT) with Technetium-99m hexamethyl propylenamine oxime (Tc-99m-HMPAO) was used in 20 patients with mild to moderate traumatic brain injury (TBI) to evaluate the effects of brain trauma on regional cerebral blood flow (rCBF). SPECT scan was compared with CT scan in 16 patients. SPECT showed intraparenchymal differences in rCBF more often than lesions diagnosed with CT scans (87.5% vs. 37.5%). In five of six patients with lesions in both modalities, the area of involvement was relatively larger on SPECT scans than on CT scans. Contrecoup changes were seen in five patients on SPECT alone, two patients with CT alone and one patient had contrecoup lesions on CT and SPECT. Of the eight patients (50%) with skull fractures, seven (43.7%) had rCBF findings on SPECT scan and five (31.3%) demonstrated decrease in rCBF in brain underlying the fracture. All these patients with fractures had normal brain on CT scans. Conversely, extra-axial lesions and fractures evident on CT did not visualize on SPECT, but SPECT demonstrated associated changes in rCBF. Although there is still lack of clinical and pathological correlation, SPECT appears to be a promising method for a more sensitive evaluation of axial lesions in patients with mild to moderate TBI.
Objective: The objective of this study is to explore adolescent non-ecigarette users' interpretations of e-cigarette advertising and their engagement with e-cigarette information. Given adolescents' lack of persuasion knowledge and the association between advertising and behaviour, insights from non-users who are heavily targeted by the industry add evidence to a field that mainly focuses on risk perceptions and reasons for experimentation. Design: Five focus groups were conducted with 39 adolescents (mean = 14.21 years, age range 12-17, 80% female). Data were analysed using the thematic approach. Results: Three themes were emerged: (1) advertising motivates nonsmokers to use e-cigarettes, (2) there is fascination with the technical and emotional appeals featured in commercials and (3) searching for information about e-cigarettes involves little validation. Adolescents also recalled health and social appeals that are consistent with content analysis of e-cigarette advertising. Further, adolescents used digital platforms and interpersonal sources for information on e-juice ingredients, health effects, accessibility, and price to satisfy their curiosity and justify their use. Very few, however, questioned the trustworthiness of the information. Conclusion: Findings provide support for the implementation of strategies, such as media literacy in public health and media campaigns, and the development of regulations vis-'a-vis advertising and access to e-cigarette products to reduce future uptake.
of legionellae are substantially more resistant to chlorine than a number of other waterborne bacteria.2 Furthermore, legionellae obtained from a hyperchlorinated hospital plumbing system seemed to be even more resistant.
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