Objective: This study sought to investigate whether the size of the target used in the horizontal vHIT has an effect on the saccade profile of healthy subjects, and to expand upon previous work linking age to the existence of small vHIT saccades. Methods: Forty eight participants were recruited between 18 and 77 years of age, with no history of vestibular, oculomotor or neurological conditions and a visual acuity of at least 0.3 LogMAR. Participants underwent four consecutive horizontal vHIT trials using the standard target size and three smaller targets. VOR gain and metrics for saccadic incidence, peak eye velocity and latency were then extracted from results. Results: Target size was a statistically significant influence on saccade metrics. As target size increased, saccadic incidence decreased while peak eye velocity and latency increased. However, a potential order effect was also discovered, and once this was corrected for the remaining effect of target size was small and is likely clinically insignificant. The effect of age was much stronger than target size; increasing age was strongly positively correlated with saccadic incidence and showed a medium size correlation with peak velocity, though not with saccadic latency. Conclusion: While this study suggests that target size may have a statistically significant impact on the vHIT saccade profile of normal subjects, age has a greater influence on the incidence and size of small vHIT saccades.

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In the initial TEOAE screening, 46 (30.7%) infants were found to have a hearing impairment. Out of which, 31 (20.7%) were confirmed to have hearing impairment after testing with AABR. 26 infants (50.9%) in the at-risk category (n=51) were found to have a hearing impairment. 86.7% of infants with exchange transfusion-requiring hyperbilirubinemia, and 70% of very low birth weight infants had a hearing impairment. ConclusionOur study shows the high prevalence of hearing loss in at-risk infants. It highlights that universal two-stage hearing screening is feasible and necessary to implement in the resource-poor rural regions of India, especially in at-risk infants.Out of 46 detected with hearing impairment in our study, 26 were in the JCIH high-risk category, whereas 20 were not. This finding highlights that screening according to the JCIH high-risk registry (HRR), as is currently prevalent in numerous resource-limited Indian healthcare settings, could miss a significant number of cases. More research in this domain is warranted to elaborate on the additional risk factors apart from those included in the JCIH HRR.TEOAE Machines should be made available and accessible at all primary and rural health centres. Training of health care staff and professionals is essential for achieving an efficient screening programme.