Background: Sleep disturbance is a disorder that includes a lack of quantity and quality of sleep. Students, especially medical students, have a high risk of getting sleep disorders of poor sleep quality and quantity. Poor sleep quality can interfere with memory. Besides, poor sleep quality also results in fatigue, which can lead to increased reaction time.Aim: To determine the relationship between sleep quality and short-term memory and reaction time in first-year medical students of Diponegoro University.Methods: This Observational study used a cross-sectional design with first-year medical students of Diponegoro University as the subjects. Kolmogorov-Smirnov was applied as the normality test, then the hypothesis test between sleep quality and short-term memory used the Pearson Chi-Square test, while sleep quality and reaction time used the Mann-Whitney U test. Results: Two hundred students participated in the study. Eighty two people (41%) had good sleep quality, 118 people (59%) had poor sleep quality. The p value of the relationship between sleep quality and short-term memory showed insignificant result (p=0.791). Meanwhile, the Mann-Whitney test to measure the relationship between sleep quality and reaction time was also insignificant (p=0.270).Conclusion: There is no significant relationship between sleep quality with reaction time and short-term memory in first-year medical students of Diponegoro University.

Gas pollutants that accumulate in the room with restricted air circulation may cause respiratory system disorders. A pregnane glycoside compound from Sansevieria can reduce the pollutants. This study aims at producing gels from Sansevieria extract to neutralize indoor gas pollutants. Sansevieria extract is produced by the maceration process with composition 8 g simplicia and 100 ml ethanol 96%. The extract was processed into the gel with a 20% concentration. The gel was applied to rats (Rattus norvegicus) Wistar strain induced by cigarette, coal, and mosquito smoke with positive control and treatment groups. After 8 days, the Gross examination and histopathology of lungs and liver were observed quantitatively. MDA levels were measured with the TBARS method. Data were analyzed by independent sample T-test and Mann-Whitney test with p-value considered significant if <0,05. Gross examination of lungs showed a significant difference between the treatment and control group that was induced by coal smoke (p=0.031), and mosquito smoke (p=0.006), and the liver’s gross of cigarette smoke (p=0.040). Histopathology of lungs showed a significant difference in mosquito smoke (p=0.032) and no significant difference in histopathology of the liver. MDA levels showed significant difference in coal smoke (p=0.020) and mosquito smoke (p=0.000). In conclusion, anti pollutant gel reduces MDA levels and damage of the lungs induced by pollutants.

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Background: Dental caries is a multifactorial illness caused by bacteria. Lactobacillus acidophilus is one of the bacteria causing caries, where it continues the caries process. That is why the antibacterial agent is needed. A cherry (Muntingia calabura) is fruit having many benefits for health, which one of them is as an antibacterial agent. It contains flavonoid, tannin, alkaloid, and terpenoid, which can function as the antibacterial agent.  Aim :The study aimed to determine the influence of cherry (Muntingia Calabura) extract in preventing the growth of L.acidophilus. Method: True experimental laboratory with a post-test only control group design and 24 samples. Cherries were extracted by using maceration. Then, the phytochemical test was conducted to discover antibacterial substances. The antibacterial test was done by using the dilution method to know Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Results: Minimum Inhibitory Concentration (MIC) could not be seen, and Minimum Bactericidal Concentration (MBC) showed that all concentration 6,25%, 12,5%, 25%, and 50% and positive control were able to kill a bacterium L. acidophilus. Conclusions: There is an influence of cherry extract on the grow

Diabetic ulcers is one of diabetic complications often experienced by patients with diabetes mellitus (DM). This problem lead to serious condition which usually have an effect on patients' quality of life. Application and research about wound care management in diabetic ulcer, specifically in ozone and olive oil, have been done already. However, exploration of how does the therapeutic effect of ozonized olive oils still limited. The purpose of this literature review is to determine the effectiveness of ozonized olive oil as topical treatment in diabetic ulcer. Source of databases in this literature review are Science direct, PubMed, and Google scholar. Articles were limited for 10 years from January 2009 to May 2019 which can be accessed full text in English. Type of literature included were review articles and research articles which the research area is in human. A qualitative analysis was performed to interpret the data. There were 5847 articles based on the keywords. Four studies met the inclusion criteria then were analyzed. Results of this review stated that it has been recently proved that ozonized olive oils are effective to care diabetic ulcer. It is useful as antiseptic, anti-fungal, topical antibiotics, anti-infections, and continued to be healing stimulator. This review provides clinical evidence which supports and recommends the benefits of ozonized olive oil in diabetic ulcer healing.

Introduction : Explosive power are the combination maximum strength and maximum velocity. High value of muscle strength and velocity can lead to good measurement of explosive power. Plyometrics training known as an exercise that can increased explosive power. This exercise is really popular among athletes and has proven to increase their explosive power. However, there’s still no further study that measured explosive power on medical students after given plyometrics training treatment. Methods : Quasi experimental study of plyometrics training has done for 6 weeks to medical students Diponegoro University. 28 subjects was divide into 2 groups : plyometrics training (as treatment group) and control group (as non-treatment group). Vertical jump test score was measurement in pre-test, middle-test, and post-test. The explosive power measured by vertical jump test. The results were analyzed by SPSS software. Results : The explosive power improved among subjects in plyometrics treatment group. During the plyometrics treatment, vertical jump was singnificantly increase during treatment in pre-test to mid-test (35.93 cm to 49,21 cm ; P : <0.001) and mid-test to post-test measurement (49.21 cm to 54.21 cm ; P : <0.001). Vertical jump score significantly increase in plyometrics group compare to control group ; on middle-test (<0.001 vs 0.344 ; P 0.019) and post-test (<0.001 vs 729 ; P 0.001) measurement respectively. Conclusions : Plyometrics training improved lower limb explosive power in male medical students of Diponegoro University. This is marked by significantly increase among subjects in plyometrics treatment group.Keywords: Plyometrics Training, Explosive Power, Vertical Jump Test

Background: Muscle explosive power as a component of physical fitness is an important factor that supports athletic performance in most sports. jump height and vertical jump performance in assessing explosive muscle power are influenced by various factors, including physiological, biomechanical, and anthropometric factors. Body mass index, muscle mass, and fat mass are important anthropometric factors in supporting jumping performance.Objective: To analyze the relationship between body mass index and muscle mass with legs muscle explosive power in first-year medical students of Diponegoro University.Methods: This study is an observational analytic study with a cross-sectional design. The subjects consist of 60 males and 108 females in first-year medical students of Diponegoro University who met the criteria. Body mass index and muscle mass were measured by Omron bioelectrical impedance analyzer, and muscle explosive power was measured by vertical jump test. Data were analyzed with the Kolmogorov Smirnov normality test and Spearman correlation test.Results: The average value of body mass index was 21.760±2.7734, muscle mass was 29.468±4.3283, and muscle explosive power was 29.468±4.3283. Muscle mass was positively correlated with legs muscle explosive power (p=0.00, R= 0.583) and negatively correlated between body mass index and legs muscle explosive power but it was not statistically significant (p=0.823 dan R=- 0.017) in first-year medical students of Diponegoro University.Conclusion: Muscle mass was positively correlated with legs muscle explosive power and body mass index showed no significant correlation with muscle explosive power. Keywords: body mass index, muscle explosive power, muscle mass, vertical jump test

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