Sulphur is a non metal element which commonly known as Gandhak. It occurs in the nature in the form of pure sulphur, sulphides and sulphates. It plays an imperative role for the maintains of health as skin, connective tissues, muscles, bones, teeth and hair, also control the metabolic process which is a key factor for the body. In nutritious substance sulphur is also found such as garlic, onion, fish and beans. Mainly sulphur is used for the cosmetic purposes as treatment of various skin diseases viz; Jarb, Qooba, Kharish, Taqassure Jild, Qarha Muzmina, Busoore Labnia etc. Unani Attiba describe it’s uses in classical text under the caption of amraze jildia.
Primary knee osteoarthritis is an extremely common cause of disability of lower extremities which results due to breakdown and destruction of joint tissues. The present study was designed to evaluate the efficacy of Majoon Yahya bin Khalid and local application of Roghan Darchini in management of Primary Knee Osteoarthritis. It was an open label evaluation study for the duration of 30 days carried out on 30 patients aged between 35 to 60 years at NIUM hospital, Bengaluru, from April 2014 to Feb 2015. After taking written voluntary informed consent, test drugs Majoon Yahya bin Khalid was given 9 gm orally twice a day, and Roghan Darchini 2-3 ml for local application on the affected knee joints once a day. Subjective as well as objective parameters were evaluated at baseline, 15th and 30th day. The results were analyzed using paired proportion and paired student t tests. Significant improvement was observed in subjective parameters of joint pain and restriction of movements with p <0.001. All the five subscales of objective parameter (Knee Osteoarthritis Outcome Score) were found to be highly significant with p <0.001. The study revealed that the test drugs are effective and safe in management of primary knee osteoarthritis.
Dyslipidaemia is a leading medical problem affecting overall health status of an individual. Deranged levels of lipid profile are responsible for atherosclerosis which ultimately leads to development of vascular diseases. If left untreated, it may result in various life threatening complications. Objective was to compare and evaluate the efficacy of test drug Qurs-e-Luk with control drug "Lipotab" in the management of Dyslipidaemia. It was a single blind, randomized, controlled, clinical trial. Thirty subjects of dyslipidaemia were selected and randomly assigned to test (20 patients) and control group (10 patients). Qurs-e-Luk and Lipotab were given to test and control groups in the form of powder (5 gm twice a day) and tablet (2 tablets per day) respectively for 60 days. All the patients of both groups were assessed on subjective and objective parameters at the baseline and after completion of trial, and the study outcome was analyzed using appropriate statistical tests. The test drug showed significant effect on few subjective and objective parameters in comparison to control drug without any significant side effects or toxicity. In test group, improvement in palpitation, fatigue and reduction in S. triglycerides and LDL was statistically significant (p < 0.05). The study infers that the comparative analyses of both drugs was not statistically significant; although improvement in subjective parameters was noted in both groups, and the effect on objective parameters was observed only in test group.
Scabies is a contagious skin disease, caused by Sarcoptes scabiei which affects around 300 million populations every year globally affecting mostly the children; but can occur in any age group and the incidence is similar in both sexes. The present clinical trial was designed to evaluate the efficacy of Zimad-e-Jarb in the management of Jarb on scientific parameters. It was a single blind randomized controlled study and was conducted on 30 patients of Jarb at National Institute of Unani Medicine, Bangalore. Participants fulfilling the inclusion criteria were included in the study, and were randomly allocated into Group A (n=20) and group B (n=10). Zimad-e-Jarb and 5% Permethrin lotion was given to the Group A and group B for 7 days and one day respectively as locally. Assessments were carried out on subjective & objective parameters weekly three times using arbitrary scale and VAS (pruritus) respectively. The result was analyzed statistically and both the drugs had significant effect on objective parameters (p<0.01). However control drug has shown more pronounced effect than test drug and no side effect was observed during and after the study. The study revealed that Zimad-e-Jarb is effective in Jarb in terms of itching, erythema, papules and number of lesions without any side effect. Therefore, it may be concluded that the test drug is safe & effective in management of Jarb.
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