Therapeutic Evaluation of Zimad-E-Jarb in Jarb (Scabies): A Single Blind Randomized Controlled Study

Abstract

Scabies is a contagious skin disease, caused by Sarcoptes scabiei which affects around 300 million populations every year globally affecting mostly the children; but can occur in any age group and the incidence is similar in both sexes. The present clinical trial was designed to evaluate the efficacy of Zimad-e-Jarb in the management of Jarb on scientific parameters. It was a single blind randomized controlled study and was conducted on 30 patients of Jarb at National Institute of Unani Medicine, Bangalore. Participants fulfilling the inclusion criteria were included in the study, and were randomly allocated into Group A (n=20) and group B (n=10). Zimad-e-Jarb and 5% Permethrin lotion was given to the Group A and group B for 7 days and one day respectively as locally. Assessments were carried out on subjective & objective parameters weekly three times using arbitrary scale and VAS (pruritus) respectively. The result was analyzed statistically and both the drugs had significant effect on objective parameters (p<0.01). However control drug has shown more pronounced effect than test drug and no side effect was observed during and after the study. The study revealed that Zimad-e-Jarb is effective in Jarb in terms of itching, erythema, papules and number of lesions without any side effect. Therefore, it may be concluded that the test drug is safe & effective in management of Jarb.

Neela Thotha (Copper sulphate): An important mineral drug of Unani medicine to be used in the management of various ailments

“…The study revealed that Zimad-e-Jarb is effective in Jarb (Scabies) in terms of itching, erythema, papules and number of lesions without any side effect 34. Wang and Borison were concluded a study that copper sulphate has emetic property35 .…”