Introduction: Common variable immunodeficiency and X-linked agammaglobulinaemia are primary immunodeficiencies classified as antibody deficiencies, and they both result in hypogammaglobulinaemia. Objective: Evaluate the lipid profile and other cardiovascular risk biomarkers in CVID and XLA patients. Methods: In total, 24 patients and 12 healthy controls matched by age and gender were included in the study. We evaluated anthropometric measurements, and seric total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), triglycerides (TG), apo A-I, small dense LDL (sdLDL), C-reactive protein (CRP), and tumour necrosis factor alpha (TNF-alpha), myeloperoxidase (MPO), cholesteryl ester transfer protein (CETP), and lecithin cholesterol acyltransferase (LCAT) were assessed. Results: CRP (p = 0.008) and TNF-alpha (p < 0.001) concentrations were significantly higher, whereas HDL-c (p = 0.025) and apo A-I (p = 0.013) levels were significantly lower in patients than in the controls. In the patient group, a negative and significant correlation was observed between HDL-c and TNF-alpha (r = -0.406; p = 0.049) and between HDL-c and TG (r = -0.641; p = 0.001). Conclusion: Common variable immunodeficiency and X-linked agammaglobulinaemia patients presented themselves with increased inflammatory markers associated with a decreased HDL-c and apo A-I levels, which can predispose to a high cardiovascular risk.
Objective: To verify the type of milk consumed by children under one year of age and identify variables associated with non-maternal milk consumption (formula or cow milk). Methods: Cross-sectional study developed during the 2012 National Vaccination Campaign against Poliomyelitis. The companions of 935 children under one year of age answered a structured questionnaire on the child’s diet in the last 24 hours. The estimates are presented by points, with 95%CI. F-statistics were used to check for differences in the proportion of the types of milk consumption according to the children’s age range (<6 months and 6-11 months) and the association between non-maternal milk consumption and the study variables. Results: The consumption of maternal milk and child formula was higher for children under six months of age - corresponding to 82.8% (95%CI 78.5-86.3) and 70.4% (95%CI 61.4-78.0), respectively -, whereas the consumption of cow milk was higher among children between 6 and 11 months of age - 74.2% (95%CI 66.5-80.6) -, with differences in the consumption proportions (p<0.0001). The variables associated with higher cow milk consumption were lower maternal education (p<0.0001), the fact that the mother does not have a paid occupation (p=0.0015), child doctor’s appointment in the public health network (p<0.0001) and participation in the Child’s Milk Program (p<0.0001).Conclusions: The infants received cow’s milk early (before the first year of life), especially children from families with lower socioeconomic levels and children who took part in a specific social program for milk distribuition.
A prevalência da obesidade tem crescido e representa um problema de saúde pública. O objetivo dessa pesquisa foi avaliar a relação entre a alimentação complementar e a prevalência de sobrepeso/ obesidade em duas escolas de Imbituva-PR, sendo uma pública e outra particular. Caracterizase por um estudo transversal que avaliou o estado nutricional de 45 crianças de 4 a 6 anos de idade. A análise estatística foi realizada pelo Software SPSS 16.0. A média do IMC foi de 16,71 ± 1,968 (kg/m²). Apenas 15 (33,3%) crianças foram amamentadas exclusivamente até o sexto mês de vida e esse não se mostrou um fator de proteção para sobrepeso/obesidade (p=1,00). O tempo de aleitamento materno menor que um ano apresentou associação estatisticamente significativa com sobrepeso/obesidade (p=0,027). A alimentação complementar não apresentou significância estatística quando comparada com sobrepeso/obesidade, entretanto foi precoce em quase todas as crianças pesquisadas. Descritores ABSTRACTThe prevalence of obesity has been increasing and it represents a public health issue. The aim of this research was to evaluate the relation between the complementary feeding and the overweight/ obesity prevalence in two schools from Imbituva-PR, a public one and a private one. It is characterized as a transversal study that evaluated the nutritional condition of forty-five children from 4 to 6 years old through anthropometric measures. The statistical analysis was performed using the SPSS 16.0 software. The average BMI was of 16.71 ± 1,968 (kg/m²). Only 15 (33,3%) children were exclusively breastfed until the sixth month of life and it did not prove to be a protective element against obesity. The breastfeeding that has lasted less than one year showed a significant statistical association with overweight/obesity (p=0,027). The complementary food did not present significant statistical results when compared to overweight/obesity. However, obesity was precocious in nearly all children studied.
Introdução: Comparar as prescrições realizadas por nutricionistas e médicos pediatras, sobre a alimentação complementar para crianças menores de dois anos e comparar com Guia Alimentar para menores de dois anos, desenvolvido pelo Ministério da Saúde (2005). Métodos: Estudo transversal realizado com profissionais do município de Guarapuava – Paraná. O instrumento utilizado foi um questionário relacionado a alimentação complementar adaptado do estudo desenvolvido por Matos (2011). Para os dados obtidos, foi realizada análise estatística. Resultados: Participaram 6 nutricionistas e 12 pediatras. Em relação as recomendações realizadas pelos profissionais, destaca-se a introdução dos cereais e sucos, os quais divergem em relação as recomendações na ordem de prescrição. Já para as demais itens avaliados não houve diferença significativa entre as recomendações realizadas. Discussão: Verificou-se que não houve diferença significativa entre as orientações. E ainda, os profissionais realizam as orientações nutricionais em acordo com o guia o que implica na introdução correta da alimentação complementar.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.