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The development of energy harvesting devices can not only effectively extend the service life of electronic equipment, but also bring convenience to equipment with power supplies that cannot be changed easily. Although the existing green energy sources can provide power to electronic devices efficiently, it is difficult to apply them to micro and small electronic devices with power on the order of mW or µW because of their demanding use conditions and large power generation. For these reasons, the energy generated by mechanical vibration and human movement has become a popular energy choice for microelectronic devices. [7-10] At present, there are several ways to convert the mechanical energy generated by vibration or moving objects into the electrical energy required by electronic equipment, including electromagnetic, [11,12] electrostatic, [13,14] and piezoelectric effect. [15,16] Compared with electromagnetic and electrostatic techniques, piezoelectric materials stand out because of their high energy conversion efficiency and strong piezoelectric sensitivity. [17,18] They can directly convert the applied mechanical stress into available electrical energy and are easy to integrate into the system, thus attracting extensive attention. These materials have been applied in many fields such as piezoelectric sensors, [19,20] actuators, [21,22] ultrasonic transducers, [23,24] and energy harvesters. [25,26] From this, we can see that piezoelectric materials show great development potential for emerging functional materials and have become the focus of future research regarding renewable clean energy and advanced energy storage materials. [27] The traditional piezoelectric device is fabricated by subtractive manufacturing. This process is not only complicated, long production cycle, low utilization rate of materials, high manufacturing cost, but it also mainly employs cutting technology such as scribing, broaching, sawing, or etching for piezoelectric devices with complex geometric shapes, which greatly limits operating conditions, density and work surroundings of piezoelectric devices. In addition, the mechanical stress generated by the traditional process will cause grain loss, strength degradation,

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Incorporation of CuS nanoparticles into the framework of ZIF-8 provides a chance to integrate near-infrared (NIR) light/low pH triggered release and chemo-photothermal therapy into one system. For the first time, we observed that the framework of ZIF-8 could be disintegrated at pH 7.4 under NIR laser irradiation.

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Aptamers are short non-coding, single-stranded oligonucleotides (RNA or DNA) developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX) in vitro. Similar to antibodies, aptamers can bind to specific targets with high affinity, and are considered promising therapeutic agents as they have several advantages over antibodies, including high specificity, stability, and non-immunogenicity. Furthermore, aptamers can be produced at a low cost and easily modified, and are, therefore, called “chemical antibodies”. In the past years, a variety of aptamers specifically bound to both breast cancer biomarkers and cells had been selected. Besides, taking advantage of nanomaterials, there were a number of aptamer-nanomaterial conjugates been developed and widely investigated for diagnostics and targeted therapy of breast cancer. In this short review, we first present a systematical review of various aptamer selection methods. Then, various aptamer-based diagnostic and therapeutic strategies of breast cancer were provided. Finally, the current problems, challenges, and future perspectives in the field were thoroughly discussed.

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