Radiologic and pathoanatomic findings in two patients with the very rate primary osteoliposarcoma of bone are reported. In one case, there was a manifestation on the left femoral shaft which led to pathologic fracture. Amputation of the femur was followed by a 2.5-year tumor-free interval. In the second case, there was a manifestation in the region of the right upper part of the ilium. After radiation and cytostatic therapy, pronounced intratumoral ossifications occurred and the patient's condition was good up to exitus lethalis 3 years after diagnosis. Osteoliposarcoma thus shows a markedly more favorable prognosis than the osteosarcoma and rather corresponds to that of a liposarcoma. Typical clinical and radiologic symptoms are lacking.
Three patients with industrial exposure to PVC are described, who developed angio-sarcomas of the liver; in one patient this was combined with a multi-lobular primary hepato-cellular carcinoma. The epidemiology, clinical features and diagnosis are discussed, with particular reference to angiography, sonography and computerized tomography. The non-invasive methods, such as computerized tomography and sonography, are the techniques of choice if an angiosarcoma is suspected after long exposure to PVC.
The sonographic morphology of benign and malignant primary and secondary tumours of the liver has been studied in 153 patients who had been investigated histologically. Eight sonographic appearances have been distinguished: Circumscribed tumours, which may be echo-free, with a faint echo, a homogenous strong echo, strong central echo with faint marginal echo, faint echo with strong marginal echo, strong with acoustic shadowing or a combination of various types; there may be diffuse tumour infiltration. Some correlation between sonographic patterns and tumour type can be recognised. However, unequivocal agreement between sonographic appearances and histological findings has not been established. Nevertheless, the various sonographic appearances of intrahepatic tumours provide valuable information concerning tumour architecture; in conjunction with clinical information this makes a diagnosis possible in a proportion of cases.
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