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We used immediate post-operative in vivo three-dimensional computed tomography to compare graft bending angles and femoral tunnel lengths in 155 patients who had undergone single-bundle reconstruction of the anterior cruciate ligament using the transtibial (n = 37), anteromedial portal (n = 72) and outside-in (n = 46) techniques. The bending angles in the sagittal and axial planes were significantly greater but the coronal-bending angle was significantly less in the transtibial group than in the anteromedial portal and outside-in groups (p < 0.001 each). The mean length of the femoral tunnel in all three planes was significantly greater in the transtibial group than the anteromedial portal and outside-in groups (p < 0.001 each), but all mean tunnel lengths in the three groups exceeded 30 mm. The only significant difference was the coronal graft- bending angle in the anteromedial portal and outside-in groups (23.5° vs 29.8°, p = 0.012). Compared with the transtibial technique, the anteromedial portal and outside-in techniques may reduce the graft-bending stress at the opening of the femoral tunnel. Despite the femoral tunnel length being shorter in the anteromedial portal and outside-in techniques than in the transtibial technique, a femoral tunnel length of more than 30 mm in the anteromedial portal and outside-in techniques may be sufficient for the graft to heal.

To the best of our knowledge, no reports have directly compared synovial fluid (SF)- and synovial membrane (SM)-derived mesenchymal stem cells (MSCs) from primary knee osteoarthritis patients in terms of MSC proportion, either immediately after isolation or during culture. Any possible correlation between SM- and SF-MSC purity and osteoarthritis severity, also remains unclear. We therefore assessed quantitative and phenotypic differences in MSCs isolated from SF and SM. We also evaluated the correlation between sample MSC purity, and disease severity, in patients with osteoarthritis. The main result of the current study was that the mean SF-MSC proportion at passage 0 was negatively correlated with Kellgren-Lawrence (KL) grade (r = -0.565, P = 0.002). In addition, KL grade was a only significant independent negative predictor of SF-MSC proportion at passage 0 (β = -0.356, P = 0.039). Conclusively, the proportion of SF-MSCs in fresh samples, evaluated at the single cell level, was inversely correlated with osteoarthritis severity.

We report the first double differential cross sections of two charged pions and kaons (e + e − → hhX) in electron-positron annihilation as a function of the fractional energies of the two hadrons for any charge and hadron combination. The dependence of these di-hadron cross sections on the topology (same, opposite-hemisphere or anywhere) is also studied with the help of the event shape variable thrust and its axis. The ratios of these di-hadron cross sections for different charges and hadron combinations directly shed light on the contributing fragmentation functions. For example, we find that the ratio of same-sign pion pairs over opposite-sign pion pairs drops toward higher fractional energies where disfavored fragmentation is expected to be suppressed. These di-hadron results are obtained from a 655 fb −1 data sample collected near the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e + e − collider. Extending the previously published single-pion and single-kaon cross sections, single-proton (e + e − → pX) cross sections are extracted from a 159 fb −1 data sub-sample.

We report on the first observations ofB 0 → D1(2430)− decay is also observed. The branching fraction measurements are based on (771.6 ± 10.6) × 10 6 BB events collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e + e − collider. The fractions of longitudinal polarization of the D * * states as well as partial wave fractions of the D1(2430) 0 are obtained. We also set a 90% confidence level upper limit for the product of branching fractions ofThe measurements show evidence of nontrivial final-state interaction phases for the ρ-meson-like amplitudes.

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We present an analysis of the semi-inclusive decays Bs → D

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