North east India is the richest reservoir of plant diversity in India and one of the 'biodiversity hotspot' of the world. Tripura, which is a hilly state of this region, is also rich in plant diversity. North Tripura district of Tripura is comprising of mostly forest area and of which 82.67 % population living in rural areas has high practices of traditional medicine for different disease conditions. This study on folk medicinal practice was done in order to document the existing folk drugs and treatment procedures among the peoples of North Tripura district of Tripura with a view to provide lead material for the discovery of new drugs of natural origin. For this local health practitioner, village head, elderly experienced persons were interviewed during 2012-2013 in the medico-ethno botanical survey of North Tripura and folk medicinal claims were documented. Present study reveals first-hand information on 48 folk medicinal claims having plant parts, animal products and minerals. Enumeration of the claims were arranged according to disease condition wise providing information on scientific names of the used folk drugs followed by local name, Sanskrit name, parts used, method of use with dose and duration as informed by the claimants and their relevant properties as per Ayurvedic texts. The documented folk medicinal claims have both single herb preparation and compound formulations.
The paper highlights some of the most important Ayurvedic medicinal plants of North Eastern India having anticancer potential. A brief review of distribution and pharmacological study (both in vivo and in vitro) of ten Ayurvedic medicinal plants of the region published by various researchers is illustrated in this paper. The medicinal plants discussed here are Enhydra Fluctuans Lour (Sanskrit: Hilamochika), Ageratum conizoides Linn.
Psoriasis is a complex, chronic, multifactorial, inflammatory disease which involves hyper proliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate. At present time, Psoriasis is one of the most common human skin diseases. Majority of the dermatological disorders have been described under the roof of Kushtha in Ayurveda. In this article, ancient Indian literature regarding dermatological disorders is studied thoroughly to make a comparison between the information given in ayurvedic classical texts and those given in modern medical science in relation to psoriasis. After studying Kustha in ayurvedic literature, it is clear that the disease Psoriasis is mostly comparable with two varieties of kshudrakustha ie. Eka kustha and Kitibha kustha and also with a variety mahakustha i.e., Sidhma kustha. It is also clear from the study that there is vast resemblance between the Panchanidan i.e., Nidan, Purvarupa, Rupa, Upasaya, Samprapti of Kustha and the etiopathogenesis and symptomatology of psoriasis. The objective of this review is successful in comparing psoriasis with kustha with special reference to Ekakustha and Kitibha kustha. Due to the close resemblance, it is also tried in this work that the treatment procedures along with various formulations mentioned in skin disorders of ayurveda can be applied in psoriasis which adds new dimensions in management of such a chronic and complex disease.
India has rich diversity of medicinal plants. The tribal peoples in different parts of India use their traditional knowledge in their primary health care. This traditional system of medicine serves a large portion of rural population which is out of reach and infrequently intruded by modern health care system. Mizoram, one of the North eastern states of India positioned in extreme of Himalayan ranges is rich in flora and fauna. There is high prevalence of folk medicinal practice in the rural areas of the state. 14 such folk medicinal claims of herbal origin documented from Lunglei and Darlawn area of Mizoram have been presented in this study.
This study is carried out in a view to evaluate hypoglycaemic activity of stem bark extracts of Annona reticulata L. in streptozotocin induced diabetic rats. Oral administrations of petroleum ether, chloroform, ethyl acetate and ethanol extract of the plant stem bark up to 2000mg/kg body weight did not show any signs of toxicity and mortality in this study. In Oral Glucose Tolerance Test, administration of glucose (2.5g/k g,) produced significant change in blood glucose level of normal mice. Treatment with A. reticulata ethanolic extract (200 and 400mg/kg) and standard drug glibenclamide (10mg/kg.) significantly reduced serum glucose level in normal fasting, at 0min, 30min, 60min and 120min compared to normal c ontrol group. Ethanolic extract of the plant showed more significant blood glucose lowering activity at 400mg/kg dose level. But Petroleum ether, ethyl acetate and chloroform extracts of the plant did not show significant decrease in the blood glucose levels. So, in this study 400mg/kg o f ethanolic extract of A. reticulata was selected for the evaluation of anti-diabetic activity in streptozotocin induced diabetic rats. Oral administration of ethanolic plant extract of A. reticulata stem bark at 400mg/kg/day and standard drug Glibencamide for 15 consecutive days to streptozotocin induced diabetic rats significantly reversed decreased body weight, increased water consumption and increased fasting plasma glucose level in comparision to diabetic control animals. Phytochemical analysis of the plant sample showed the presence of different chemical compounds like alkaloids, flavanoides, Phenolic glycosides and lignans.
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