Self-medication is very common among people of all ages, usually through nominations from third parties, self-knowledge or easy access in pharmacies. The objective of the study was to evaluate and verify the prevalence of self-medication for the treatment of pain in patients seen in campaigns conducted by Universidade do Oeste Paulista. A questionnaire was applied involving socio-demographic aspects, drug use, the practice of self-medication and types of pain. The sample consisted of 248 participants, where 203 admitted the use of non-steroidal anti-inflammatory drugs(AINEs). Of these 203, 166 (81.7%) reported self-medication, being dipyrone (48.5%) and paracetamol (21.1%), themost frequently mentioned AINEs. The headache was more prevalent in women 99 (26.8%) and men 51 (13.8%), being womenconsidered the ones who most read the package leaflet 70 (34.5%) and know the effects adverse effects of the same 49 (24.2%). It can be concluded that the practice of self-medication is very frequent in the studied population.
Heart failure (HF) is an inability of the heart to surprise tissue metabolism. The Brazilian Society of Cardiology, in 2020, 100 thousand new public health diagnoses and a rate of 50 thousand citizens/year, configuring a public health problem. Therefore, compare the diligence of Angiotensin Converting Enzyme Inducers (ACEI) and Angiotensin Receptor Blockers (ARB) in HF, for results: clinical stability, hospitalizations and deaths. Searches of 1789 randomized clinical trials were carried out on the platforms: Cochrane, PubMed and LILACS, based on indexed descriptors, with the terms MESH/Decs, of which 8 were in full. Perindopril functional hospitalization (HR 0.928; P 0.033), mortality (HR 0.98; P 0.928) and class (P 0.030). Both enalapril and candesartan reduced deaths and hospitalizations. Discontinuation of ACEI/ARB increased 4-fold mortality in 180 days. Therefore, there is evidence of therapeutic equivalence among the drugs analyzed in the CI.
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