Objective: This study sought to identify the presence of HPV infection and the risk factors related to susceptibility to cervical cancer in asymptomatic women. Methods: It is a cross-sectional study with 428 users attended Basic Health Units, in Arapiraca, Alagoas, Brazil. Sociodemographic, behavioral variables, and cytopathological reports were collected. Molecular detection of the HPV virus was performed by Nested-PCR. Statistical analysis was conducted with SPSS version 22.0. Results: A total of 428 women were studied, HPV DNA detected in 39.2% (n = 168), with a mean age of 41 years old. There was an association of HPV with use of oral contraceptives (p <0.016) and alcoholism (p <0.038). It was showed a higher frequency of positive HPV in women older than 25 years old (88.7%), up to 5 sexual partners (93.4%), up to 3 pregnancies (71.4%), and with the cytopathologic results within the limits of normality (61.9%). HPV was identified in 40.3% (104/258) of the women with results within the limits of normality. Conclusion: Our results suggest that the use of oral contraceptives and alcoholism may be considered as possible risk factors related to cervical oncogenesis. With this, it is necessary to propose interventions aimed at the health education of this population, actions of prevention, and early detection.

RESUMO Objetivo: descrever os diagnósticos de Enfermagem segundo a taxonomia da American Nursing Diagnosis Association II.  Método: trata-se de estudo quantitativo, descritivo, transversal, com 51 produtores de tabaco expostos a agroquímicos que viviam na comunidade rural. Coletaram-se os dados por meio das consultas de Enfermagem. Tabularam-se os dados n Programa Microsoft Excel 2010, posteriormente inseridos no banco de dados utilizando o programa SPSS, versão 22.0, for Windows, e submetidos à revisão e análise estatística. Apresentaram-se os resultados em tabelas. Resultados: verificou-se, por meio das consultas de Enfermagem, que a maioria era do sexo feminino, tinha ensino fundamental incompleto e não praticava nenhum tipo de exercício físico. Acrescenta-se, além disso, que eles desconheciam os riscos para a saúde colocados pelos pesticidas e negligenciaram os padrões de segurança recomendados para o manuseio desses produtos. Conclusão: pode-se observar, a partir deste estudo, que o enfermeiro tem um papel importante no cuidado e na educação, nos diversos espaços de promoção, prevenção e manutenção do cuidado em saúde. Descritores: Enfermagem; Diagnósticos de Enfermagem; Estratégia Saúde da Família; Área Rural; Saúde Pública; Saúde do Trabalhador.ABSTRACT Objective: to describe Nursing diagnoses according to the Taxonomy II proposed by the North American Nursing Diagnosis Association. Method: this is a quantitative, descriptive, cross-sectional study conducted with co plantations. The research was carried out with 51 tobacco growers exposed to agrochemicals living in the rural community. The data were collected through nursing consultations. The data collected were tabulated in the Microsoft Excel 2010 software and later entered into a database using the SPSS software version 22.0, for Windows, and subjected to statistical review and analysis. The results were presented in tables. Results: the Nursing consultations revealed that the majority of the farm workers were females, had incomplete elementary education, and did not practice any type of physical exercise. In addition, they were unaware of the health risks posed by pesticides and neglected the recommended safety standards for the handling of these products. Conclusion: it was observed in this study that nurses have an important role in care and education, in the various spaces of promotion, prevention and maintenance of health care. Descriptors: Nursing; Nursing Diagnoses; Family Health Strategy; Rural Area; Public Health; Occupational Health.RESUMEN Objetivo: se buscó describir los diagnósticos de Enfermería según la taxonomía de la American Nursing Diagnosis Association II. Método: se trata de un estudio cuantitativo, descriptivo, transversal, realizado con 51 productores de tabaco expuestos a agroquímicos que vivían en la comunidad rural. Se recogieron los datos por medio de las consultas de Enfermería. Se tabularon los datos recogidos en el programa Microsoft Excel 2010, posteriormente inseridos en el banco de datos utilizando el programa SPSS, versión 22.0, for Windows, y sometidos a la revisión y análisis estadística. Se presentaron los resultados en tablas. Resultados: se verificó, por medio de las consultas de Enfermería, que la mayoría era del sexo femenino, tenía enseñanza primaria incompleta y no praticaba ningún tipo de ejercicio físico. Además de eso, ellos desconocen los riesgos para la salud colocados por los pesticidas y negligenciaron los patrones de seguridad recomendados para el manoseo de esos productos. Conclusión: se puede observar, a partir de este estudio, que el enfermero tiene un papel importante en el cuidado y en la educación, en los diversos espacios de promoción, prevención y mantenimiento del cuidado en salud. Descriptores: Enfermería; Diagnósticos de Enfermería; Estrategia Salud de la Familia; Zona Rural; Salud Pública; Salud Laboral.

ObjectiveGreen Tobacco Sickness (GTS) is an occupational illness caused by dermal absorption of nicotine from tobacco leaves. It affects thousands of farm workers worldwide. Brazil is the second tobacco producer in the world; despite this, there are few studies on GTS among Brazilian harvesters. This study aimed to determine the prevalence of GTS among a population of tobacco workers from a producing area in northeastern Brazil and investigate whether the occurrence of the disease was influenced by factors such age, gender and smoking status. In addition, it was investigated if there was association between the onset of GTS and genetic polymorphisms in genes that encode some detoxification enzymes. A semi-structured questionnaire was used to collect demographic, behavioral and occupational data from the referred workers. Polymorphisms were tested through the Polymerase Chain Reaction technique.ResultsThe total prevalence of GTS found was 56.9%, with a significant difference between genders (71.7% for women and 35.3% for men, p < 0.0001). No association was identified between the investigated polymorphisms and GTS. This study confirms the occurrence of GTS among tobacco harvesters in Brazil with high prevalence. The investigation suggests the need to take preventive measures to protect tobacco workers against this disease.

O objetivo deste estudo foi destacar as evidências sobre as propriedades do extrato de Stryphnodendron adstringens (Mart.) Coville (Barbatimão) e sua aplicação à saúde humana. Para tanto, foram pesquisadas as bases de dados do Portal de Periódicos da CAPES, Scielo, ScienceDirect, PubMed e Scopus referentes ao período de 2002 a 2019. Esta é uma revisão de todos os estudos publicados desde 2002 sobre as propriedades do extrato de Stryphnodendron adstringens (Mart.) Coville (Barbatimão). Embora estudos in vitro e in vivo tenham demonstrado propriedades anticâncer, antimicrobianas, antivirais, fúngicas, antiinflamatórias e cicatrizantes. Além disso, determinadas condições clínicas também apresentaram melhora do quadro clínico com o uso do Barbatimão incluindo diminuição da glicose sérica, artrite e doença de Alzheimer.

Objetivo: Identificar a prevalência de genótipos do papilomavírus humano (HPV) e fatores de risco para o câncer cervical. Metodologia: Trata-se de um estudo descritivo do tipo caso-controle, realizado com usuárias do Sistema Único de Saúde (SUS) do município de Arapiraca, Alagoas, durante o período de 2014 a 2016. Resultados: A prevalência do HPV foi de 50,07% (355 pacientes) do total de 709 amostras analisadas. A média de idade das mulheres infectadas por HPV foi de 41,55±14,48 anos. Dentre as pacientes com HPV positivo, 82,25% (n=292) possuíam renda familiar ≤ 2 salários mínimos, 58,87% (n=209) tinham até 9 anos de estudo e 67,04% (n=238) eram fumantes. Das 60 amostras cujos tipos de HPV foram identificados, 80% (n=48) eram referentes a tipos oncogênicos e 20% (n=12) faziam parte do grupo de baixo risco. Através do sequenciamento genético foi possível identificar dezessete tipos diferentes de HPV, sobressaindo-se o tipo 16, correspondendo a 23,33% (n=14) dos casos. Ocorreu uma diferença estatisticamente significativa entre a variável renda familiar e a infecção de alto ou baixo risco por HPV (p˂0,023). Conclusão: É de extrema importância o entendimento a respeito da dinâmica do vírus em diferentes regiões, identificando possíveis diferenças em relação a prevalência e fatores comportamentais, considerando-se que diferentes populações possuem características específicas, possibilitando diferenciação na exposição. DESCRITORES: HPV. Câncer de Colo do Útero. Fatores de Risco.

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The aim of this study was to present the circulating HPV genotypes in a population from northeast Brazil. HPV was detected by nested-Polymerase Chain Reaction (nPCR) method using primers MY09/11 and GP5+/6+. HPV sequencing was performed by the method of Sanger. The HPV 16 was the most frequent (35.7%), followed by HPV 58 (14.3%). In conclusion, we identified, in one population from Northeast Brazil, a low prevalence of HPV 18 present in the vaccine provided by Unified Health System and a high prevalence of HPV 58 which is not present in this vaccine. KEYWORDS: HPV, Oncology and Woman Healthy.

To identify the incidence of human papillomavirus (HPV) with the presence of other microorganisms. This is a cross-sectional study composed of 128 women who were attended in the basic health units, between 2014 and 2018, to perform the Pap smear. The presence of papillomavirus was investigated using conventional PCR with primers MY09/11 and GP5 +/6+ (echo and endocervix cells) and the smear bacterioscopy of vaginal secretions was performed to identify the microorganisms. Statistical was performed using the square test, including a risk ratio or 95% confidence interval. HPV infection was identified in 48.4% (n = 62) women. Corynebacterium sp (39.8%) was the most prevalent microorganism, followed by Escherichia coli (21.1%), Staphylococcus aureus (14.0%), Gardnerella vaginalis (13.2%) and Candida albicans (7%), respectively. According to statistical analysis or HPV and the group of potentially pathogenic microorganisms had a significant association p <0.02. Corynebacterium sp showed an effective protection (0.356 [0.170-0.744] <0.05) in relation to sociodemographic, gynecological and obstetric factors. Only vaginal discharge and pH had p <0.05 when comparing the presence of infection. The other variables showed no statistical differences. This study revealed an association between the presence of pathogenic microorganisms with HPV virus infection, confirming a need for a better understanding of the female genitals’ microbiota. Thus, research involving the vaginal infectious agents, methods of protection and rapid diagnosis to contribute to the reduction of the number of lesions in the cervix and cervical cancer are needed.