The relevance of regional lymph node (LN) assessment to quantify the metastatic spread of cancer is well recognized in veterinary oncology. Evaluation of LNs is critical for tumour staging. However, sampling the correct LN may not be possible without sentinel lymph node (SLN) mapping. Methods for diagnostic imaging and intraoperative detection of SLNs are well established in human medicine, in particular, the combination of lymphoscintigraphy and intraoperative application of blue dyes. Nevertheless, alternative imaging techniques are available and have gained increasing interest. Successful implementation of these techniques in dogs have been reported in both clinical and experimental studies. This review aims to provide an overview of SLN mapping techniques in human and veterinary medicine.

Enteric duplication is a rare developmental malformation in people, dogs and cats. The purpose of the present report is to describe the first case of a rectal duplication cyst in a 7-year-old domestic shorthair cat presenting for acute constipation and tenesmus. On rectal palpation a spherical mass compressing the lumen of the rectum could be felt in the dorsal wall of the rectum. A computed tomography (CT) scan confirmed the presence of a well demarcated cystic lesion in the pelvic canal, dorsal to the rectum. The cyst was surgically removed via a perineal approach. No communication with the rectal lumen could be demonstrated. Histopathological examination was consistent with a rectal duplication cyst. Clinical signs resolved completely after excision of this conjoined non-communicating cystic rectal duplicate.

Glucocorticoids (GCs) are critical regulators of metabolic control in mammals and their aberrant function has been linked to several pathologies. GCs are widely used in human and veterinary clinical practice as potent anti-inflammatory and immune suppressive agents. Dyslipidaemia is a frequently observed consequence of GC treatment, typified by increased lipolysis, lipid mobilization, liponeogenesis, and adipogenesis. Dogs with excess GC show hyperlipidaemia, hypertension, and a higher risk of developing type 2 diabetes mellitus, but the risk of developing atherosclerotic lesions is low as compared to humans. This study aimed to examine alterations in the canine plasma lipidome in a model of experimentally induced short-term and long-term GC excess. Both treatments led to significant plasma lipidome alterations, which were more pronounced after long-term excess steroid exposure. In particular, monohexosylceramides, phosphatidylinositols, ether phosphatidylcholines, acyl phosphatidylcholines, triacylglycerols and sphingosine 1-phosphates showed significant changes. The present study highlights the hitherto unknown effects of GCs on lipid metabolism, which will be important in the further elucidation of the role and function of GCs as drugs and in metabolic and cardiovascular diseases.

Purpose  To describe a case of an orbito‐nasal cyst in a cat. Procedure  An 18‐month‐old male European short‐haired cat was presented to the Ophthalmology service of the Vetsuisse Faculty, University of Zurich for a subcutaneous swelling in the medial canthal region of the right eye (OD). Ophthalmologic, ultrasound and CT examinations, and fine needle aspiration were performed. After lesion excision, the removed tissue was submitted for histopathology. CT examination was repeated 5 months after removal of the cyst. Results  Ophthalmologic examination revealed a large fluctuant swelling inferonasal to OD. Despite patent lacrimal puncta, only the first few mm of the lacrimal canaliculi could be cannulated. A normal globe with moderate enophthalmos was present. Ultrasound examination showed a well‐defined lobulated cyst‐like structure in the right orbit, inferonasal and anterior to the eye. CT examination revealed extension of this lesion through the medial orbital wall into the right nasal cavity. Fine needle aspiration confirmed the cystic nature of the lesion. An orbito‐nasal cyst was diagnosed. The orbital part of the cyst was dissected from the surrounding tissue and excised from the periosteum in the medial orbital wall defect. Part of the maxillary bone was removed to allow removal of the cyst from the nasal cavity. Histologically, the cyst wall consisted of a single to multilayered, mostly cuboidal epithelium and surrounding connective tissue. Follow‐up revealed a good functional result and no recurrence 7 months after cyst removal. Conclusions  Similar orbito‐nasal cystic structures were reported in dogs but not in cats.

Prior to presentation, the dog had apathy for 3 days and vomiting for 1 day. Since then, the dog had been anorectic and become progressively apathetic. The dog presented in lateral recumbency and was becoming stuporous. Clinical findings included white, dry mucous membranes, and it was not possible to determine capillary refill time. Bounding femoral pulses were detected, and the dog had a very large, firm abdomen. The dog did not experience pain on abdominal palpation. Percussion of the abdomen was negative. The dog had a heart rate of 164 beats per minute, respiratory rate of 36 breaths per minute and a temperature of 37°C. The dog's hematocrit was 21%, and the albumin level was 31.2 g/l, both at the lower limit of normal. The white blood count was elevated at 17,800 cells/l with a left shift, and relative monocytosis and lymphopenia. The dog had no previous illnesses. Anemia and hypovolemic shock were diagnosed, and the dog was suspected of having a splenic torsion. Other differential diagnoses included gastric dilation and torsion, rupture of the gastrointestinal tract with peritonitis, abdominal hemorrhage, and pancreatitis. Radiographic and Ultrasonographic FindingsLateral and dorsoventral radiographs of the abdomen were made. The dog's discomfort prevented it from being positioned on its back, so a dorsoventral radiograph of the abdomen was obtained. The abdomen was large with generalized loss of detail. A 20-cm long heterogeneous, illdefined, space-occupying lesion that contained numerous small round to irregularly shaped gas opacities was localized to the right midventral abdomen (Fig. 1). The stomach and small intestines were not distinguishable, and further From the Depdrtment of Clinical Veterinary Medicine, Divisions of Radiology (Gaschen, Kircher, and Lang) and Surgery (Venzin and Hurter),