Investigating the interactions between nanoscale materials and microorganisms is crucial to provide a comprehensive, proactive understanding of nanomaterial toxicity and explore the potential for novel applications. It is well known that nanomaterial behavior is governed by the size and composition of the particles, though the effects of small differences in size toward biological cells have not been well investigated. Palladium nanoparticles (Pd NPs) have gained significant interest as catalysts for important carbon-carbon and carbon-heteroatom reactions and are increasingly used in the chemical industry, however, few other applications of Pd NPs have been investigated. In the present study, we examined the antimicrobial capacity of Pd NPs, which provides both an indication of their usefulness as target antimicrobial compounds, as well as their potency as potential environmental pollutants. We synthesized Pd NPs of three different well-constrained sizes, 2.0±0.1 nm, 2.5±0.2 nm and 3.1±0.2 nm. We examined the inhibitory effects of the Pd NPs and Pd2+ ions toward gram negative Escherichia coli (E. coli) and gram positive Staphylococcus aureus (S. aureus) bacterial cultures throughout a 24 hour period. Inhibitory growth effects of six concentrations of Pd NPs and Pd2+ ions (2.5×10−4, 10−5, 10−6, 10−7, 10−8, and 10−9 M) were examined. Our results indicate that Pd NPs are generally much more inhibitory toward S. aureus than toward E. coli, though all sizes are toxic at ≥10−5 M to both organisms. We observed a significant difference in size-dependence of antimicrobial activity, which differed based on the microorganism tested. Our work shows that Pd NPs are highly antimicrobial, and that fine-scale (<1 nm) differences in size can alter antimicrobial activity.

Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve agents and chemical warfare agents, such as, VX, Soman and Sarin. Unfortunately, widespread and frequent commercial use of OP-based compounds in agricultural lands has resulted in their presence as residues in crops, livestock, and poultry products and also led to their migration into aquifers. Thus, the design of new sensors with improved analyte selectivity and sensitivity is of paramount importance in this area. Herein, we review recent advances in the development of fluorescent chemosensors for toxic OP pesticides and related compounds. We also discuss challenges and progress towards the design of future chemosensors with dual modes for signal transduction.

No abstract

Controlling the nucleation and growth processes for nanoparticle synthesis allows the development of well-defined structures that offer unique chemical and physical properties. Here, we report a wet chemical reduction method for synthesizing ruthenium nanocubes (Ru NCs) that display plasmonic properties at room temperature (RT). The growth of the particles to form nanostructured cubes was established by varying the carbon chain length of the thioether stabilizing ligands and the reaction time to produce stable and controlled growth. In this study, we found that the longer the thioether chain length, the less isotropic the shape of the particles. Short chain lengths of thioethers (ethyl sulfide and butyl sulfide) produced spherical nanoparticles, whereas longer chain lengths (hexyl sulfide and octyl sulfide) produced cubic nanoparticles. In addition, parameters such as the ligand to precursor ratio also played an important role in the homogeneity of the nanocubes. The Ru NCs were characterized by UV–visible absorbance spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS), which supported a face-centered cubic (fcc) structure. Moreover, to demonstrate catalytic efficiency, we studied their ability to reduce benzaldehyde to benzyl alcohol, and the Ru NCs demonstrated an overall 78% efficiency at room temperature.

The design and synthesis of well-defined metallic and bimetallic nanoparticles (NPs), their characterization, and the assessment of how their size and shape-dependent properties influence their applications are important areas of investigation for advancing green technologies that protect the environment. This chapter reviews recent advances in the design and synthesis of metallic, bimetallic and semiconductor nanoparticles and their emerging applications in the production of energy and chemicals from biorenewable materials. This contribution focuses on nanoparticle-mediated processes for biomass transformation that include hydrogenation, hydrogenolysis, decarboxylation, small molecule oxidation, conversion of cellulosic materials, hydrocarbon formation, and production of fuel cells. These processes all have significant potential for development of green technologies.

No abstract

No abstract