Chemotherapeutic agents have been used as an adjunct to mechanical debridement for peri-implantitis treatment. The present in vitro study evaluated and compared the effectiveness of hypochlorous acid (HOCl), sodium hypochlorite (NaOCl), and chlorhexidine (CHX) at eliminating Gram-negative (E. coli and P. gingivalis) and Gram-positive (E. faecalis and S. sanguinis) bacteria. The effect of irrigating volume and exposure time on the antimicrobial efficacy of HOCl was evaluated, and a durability analysis was completed. Live/dead staining, morphology observation, alamarBlue assay, and lipopolysaccharide (LPS) detection were examined on grit-blasted and biofilm-contaminated titanium alloy discs after treatment with the three chemotherapeutic agents. The results indicated that HOCl exhibited better antibacterial efficacy with increasing irrigating volumes. HOCl achieved greater antibacterial efficacy as treatment time was increased. A decrease in antimicrobial effectiveness was observed when HOCl was unsealed and left in contact with the air. All the irrigants showed antibacterial activity and killed the majority of bacteria on the titanium alloy surfaces of biofilm-contaminated implants. Moreover, HOCl significantly lowered the LPS concentration of P. gingivalis when compared with NaOCl and CHX. Thus, a HOCl antiseptic may be effective for cleaning biofilm-contaminated implant surfaces.
Purpose -The purpose of this paper is to explore the social value of information in virtual investment communities and compare its effects with objective information value. A model including information quality, social comparison, and herding orientation, and their effects on decision usefulness and member satisfaction, is proposed and tested. Design/methodology/approach -An online survey with a sample of 215 members of investment communities was conducted to test the proposed model. Findings -The opinion comparison orientation of members and information credibility are positively related to their perceived decision usefulness and satisfaction. Consistency is positively related to decision usefulness, but not to member satisfaction. Members' herding tendency moderates the effect of opinion comparison orientation on decision usefulness and the effect of ability comparison orientation on satisfaction.Research limitations/implications -The sample is small and not random. The proportion of students in the sample seems to be higher than it should be among virtual investment community members. Practical implications -Investors should be careful regarding the social influences of their communities; the effects may not always be good for investment decisions. Social implications -Virtual communities provide members with social comparison information, which may yield positive effects for members in inspiration, self-improvement, and self-enhancement. Originality/value -The virtual community can be a forum where people gain information regarding others to satisfy their needs for social comparison. Virtual communities provide special social value for their members, even for those who do not interact with others by posting in the communities.
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