We report 4 cases of silicone intraocular lens (IOL) opacification (SI-40NB, Allergan Inc.) in patients who had phacoemulsification between April and June 2003. The opacification was observed on the first postoperative day in all cases. The appearance of the silicone IOLs ranged from milky gray to a yellow hue and affected the entire optical component homogeneously. The patients did not complain about their vision, and visual acuity was only slightly affected; 3 of the 4 patients had a best corrected visual acuity of 20/30, and no anterior chamber reaction was observed. Contrast sensitivity was reduced in all cases. Careful scrutiny of medical histories failed to reveal factors that might have predisposed the patients to IOL opacification.
Most IOLs are enclosed in semipermeable packages to allow sterilization by ethylene oxide gas. During cleaning or disinfection of storage rooms, aerosolized solutions may introduce chemicals through the package and onto the IOLs. This may cause surface changes in the IOL, promoting opacification by water ingress in the aqueous environment. Cleaning and disinfection procedures of IOL storage areas should be monitored carefully.
Mean intraocular pressure and fibrosis were lower in animals receiving bevacizumab in combination with mitomycin C but did not differ from values in animals receiving mitomycin C alone. Inhibition of VEGF was greater when bevacizumab was used alone than when bevacizumab was combined with mitomycin C.
We report a case of recurrent iris synechiae one year after Nd:YAG laser goniopuncture for deep sclerectomy enhancement in the only functional eye of a patient with end-stage glaucoma. The possible pathophysiology of this uncommon complication and laser treatment aspects are discussed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.