Early warning of weather conditions conducive to outbreaks of Ross River virus disease is possible at the regional level with a high degree of accuracy. Our models may have application as a decision tool for health authorities to use in risk-management planning.
Quantitative assessment of climatic and environmental health risks is necessary because changes in climate are expected. We therefore aimed to quantify the relationship between climatic extremes and mortality in the 5 largest Australian cities during the period [1979][1980][1981][1982][1983][1984][1985][1986][1987][1988][1989][1990]. We then applied the relationship determined between recent climatic conditions and mortality to scenarios for climate and demographic change, to predict potential impacts on public health in the cities in the year 2030. Data on mortality, denominator population and climate were obtained. The expected numbers of deaths per day in each city were calculated. Observed daily deaths were compared with expected rates according to temperature thresholds. Mortality was also examined in association with temporal synoptic indices (TSI) of climate, developed by principal component and cluster analysis. According to observed-expected threshold analyses, for the 5 cities combined, the annual mean excess of deaths attributable to temperature over the period [1979][1980][1981][1982][1983][1984][1985][1986][1987][1988][1989][1990] was 175 for the 28掳C threshold. This sum of statistically significant differences from the 5 cities was the greatest excess found in association with any threshold considered in the range of temperatures that occur. Excess mortality for the hottest days in summer was greater than for the coldest days in winter. Temperature-mortality relationships were little modified by socio-economic status. TSI analyses produced similar results: using this method, the climate-attributable mortality in the 5 cities was approximately 160 deaths yr -1 , although this number was evenly distributed across summer and winter. Persons in the group aged 65 yr and older were the most vulnerable. After allowing for increases in population, and combining all age groups, the synoptic method showed a 10% reduction in mortality in the year 2030. We conclude that the 5 largest Australian cities exhibit climate-attributable mortality in both summer and winter. Given the scenarios of regional warming during the next 3 decades, the expected changes in mortality due to direct climatic effects in these major coastal Australian cities are minor.
Objective To investigate the time relations between long haul air travel and venous thromboembolism. Design Record linkage study using the case crossover approach. Setting Western Australia. Participants 5408 patients admitted to hospital with venous thromboembolism and matched with data for arrivals of international flights during 1981-99. Results The risk of venous thromboembolism is increased for only two weeks after a long haul flight; 46 Australian citizens and 200 non-Australian citizens had an episode of venous thromboembolism during this so called hazard period. The relative risk during this period for Australian citizens was 4.17 (95% confidence interval, 2.94 to 5.40), with 76% of cases (n = 35) attributable to the preceding flight. A "healthy traveller" effect was observed, particularly for Australian citizens. Conclusions The annual risk of venous thromboembolism is increased by 12% if one long haul flight is taken yearly. The average risk of death from flight related venous thromboembolism is small compared with that from motor vehicle crashes and injuries at work. The individual risk of death from flight related venous thromboembolism for people with certain pre-existing medical conditions is, however, likely to be greater than the average risk of 1 per 2 million for passengers arriving from a flight. Airlines and health authorities should continue to advise passengers on how to minimise risk.
The effect of calcium supplementation on bone mineral density (BMD) was evaluated in female twin pairs aged 10-17 years with a mean age of 14 years. Forty-two twin pairs (22 monozygotic, 20 dizygotic; (including one monozygotic pair from a set of triplets) completed at least 6 months of the intervention: 37 pairs to 12 months and 28 pairs to 18 months. BMD was measured by dual-energy X-ray absorptiometry (DXA). In a double-blind manner, one twin in each pair was randomly assigned to receive daily a 1000 mg effervescent calcium tablet (Sandocal 1000), and the other a placebo tablet similar in taste and appearance to the calcium supplement but containing no calcium. Compliance (at least 80% tablets consumed), as measured by tablet count, was 85% in the placebo group and 83% in the calcium group over the 18 months of the study, on average increasing dietary calcium to over 1600 mg/day. There was no within-pair difference in the change in height or weight. When the effect of calcium supplementation on BMD was compared with placebo at approximately 6, 12 and 18 months, it was found that there was a 0.015 +/- 0.007 g/ cm2 greater increase in BMD (1.62 +/- 0.84%) at the spine in those on calcium after 18 months. At the end of the first 6 months there was a significant within-pair difference of 1.53 +/- 0.56% at the spine and 1.27 +/- 0.50% at the hip. However, there were no significant differences in the changes in BMD after the initial effect over the first 6 months. Therefore, we found an increase in BMD at the spine with calcium supplementation in females with a mean age of 14 years. The greatest effect was seen in the first 6 months; thereafter the difference was maintained, but there was no accelerated increase in BMD associated with calcium supplementation. The continuance of the intervention until the attainment of peak bone mass and follow-up after cessation of calcium supplementation will be important in clarifying the optimal timing for increased dietary calcium and the sustained, long-term effects of this intervention.
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