These findings contradict, at least in our older sample, the postulates of positive psychology, and support the bottom-up approach to well-being as well as the popular adage, "As long as you've got your health."

No abstract

Our findings support the importance of both modes of coping for the mental health of older adults. In particular, the ability to adjust goals was shown to be critical as a way of preventing the development of depressive symptoms following negative life events.

Juvenile Huntington disease (JHD) is a rare clinical entity characterized by disease onset before the age of 21. JHD accounts for <10% of Huntington disease patients. Transmission of JHD is paternal in 80-90% of cases. Patients with JHD usually carry more than 60 CAG repeats within the HTT gene. We report here on a 23-month-old boy presenting with global developmental delay first noted at 18 months of age. Clinical examination showed truncal hypotonia, postural and intentional tremor, limb rigidity, and ataxia. Cerebral magnetic resonance imagery (MRI) showed reduced cerebellar volume. Six months later, his 47-year-old father was seen for a 4-year history of progressive dementia with severe behavioral disturbance and chorea. Cerebral MRI showed discrete global and caudate atrophy. DNA analysis revealed a very large and heterogeneous expansion (210-250 CAG) in the child and a 43 CAG expansion of the HTT gene in the father. This unusual case demonstrates that very early onset JHD due to large CAG expansions should be considered in cases of global developmental delay associated with reduced cerebellar volume, including cases without known HD family history.

No abstract

When evaluating a product or service, consumers seek out information to judge whether that specific product will meet certain criteria. The main concern of sales providers is how to increase their purchasers' willingness to buy a product. The authors studied the impact of age on the perceived importance and interaction of three factors known to influence people when buying clothes: price, durability and suitability. A sample of 160 French adults aged 18-90 rated their likelihood of buying an item of clothing in 27 scenarios, in which three levels (low, moderate and high) of each of the above three factors were combined in an orthogonal factorial design. For younger participants, a low price was considered a sufficient reason to buy the item of clothing. For older participants, suitability was a more important factor, while for the eldest people, durability was the most important.

In line with successful aging theory, our findings support the view that the ability to adjust personal goals flexibly is a central resource when unattainable goals are encountered and it contributes to well-being in old age.

Patients' willingness to take a newly prescribed medication is an important, but little studied, part of the medication process. The authors studied the impact of patient age on the perceived importance and interaction of three factors known to influence young people: severity of their medical condition, extent of possible medication side effects, and level of trust in their physician. A convenience sample of 170 French adults aged 18 to 93 rated their likelihood of taking a medication intended to alleviate physical suffering in 27 scenarios in which three levels (low, moderate, and high) of each of the above three factors were combined in an orthogonal factorial design. Among younger participants, high trust in the physician was not considered a sufficient reason for high acceptance of a new medication; it had to be accompanied by low side effects. Among very elderly participants, high trust led to high acceptance almost irrespective of the severity of possible side effects. Among the middle aged, trust and side effects had largely independent effects. To promote patients' acceptance of newly prescribed medications, physicians need to establish trust, but not abuse its power in elderly patients.