BACKGROUND: Malnutrition is a frequent condition among hospitalized patients and a factor of increased risk of postoperative complication. OBJECTIVE: This study aimed to evaluate the impact of malnutrition on phase angle (PA), body water distribution and clinical outcomes in surgical patients with colorectal disease. METHODS: This retrospective study was performed in a tertiary hospital with 40 patients admitted electively. In the preoperative evaluation, global subjective assessment and bioelectrical impedance analysis were performed to determine nutritional status, PA, extracellular water (ECW), intracellular water (ICW) and total body water (TBW). In postoperative evaluation, the length of hospital stay and severe complications, according to Clavien-Dindo classification, were determined. The optimal PA cutoff for malnutrition screening was determined by ROC curve analysis. RESULTS: Seventeen (42.5%) patients were diagnosed as malnourished and 23 (57.5%) as well-nourished according to global subjective assessment. Twelve (30.0%) patients developed severe complications. The malnourished group presented lower values of serum albumin (P=0.012), hematocrit (P=0.026) and PA (P=0.002); meanwhile, ECW/ICW (P=0.019) and ECW/TBW (P=0.047) were higher. Furthermore, 58.8% of malnourished patients developed severe postoperative complications compared to 8.7% of well-nourished. Malnutrition was independent predictor of severe postoperative complications (OR=15.00, IC: 2.63-85.68, P=0.002). The optimal PA cutoff obtained was 6.0º (AUC=0.82, P=0.001), yielding sensitivity, specificity, positive predictive value and negative predictive value of 76.5%, 87.0%, 81.3% and 83.4%, respectively. CONCLUSION: Malnutrition was an independent predictive factor for severe complications in patients underwent to elective major coloproctological surgery. Besides that, malnutrition was associated with lower PA values and greater ratio of ECW. The PA provided great accuracy in nutritional screening, implying a useful marker of malnutrition.
BackgroundBrazil has the most extensive plant genetic biodiversity in the world. Knowledge regarding the therapeutic properties of medicinal plants obtained through popular medicine has been accrued over centuries. Such empirical knowledge often symbolizes the only therapeutic resource for various ethnic communities and groups. This study aimed to evaluate the efficacy of hydroalcoholic extracts of medicinal plants in controlling isolated fungi found in bathrooms and nurseries of a daycare center in the northwestern region of São Paulo state. MethodologyThis is an in vitro study carried out in the microbiology laboratory. The analyzed fungi were Aspergillus niger, Fusarium spp., Trichophyton mentagrophytes, Microsporum gypseum, and Candida albicans. These fungi were exposed to the hydroalcoholic extracts of rosemary, citronella, rue, neem, and lemon. ResultsRue extract was more effective against Candida albicans at a concentration of 12.5%. Citronella was effective against Aspergillus niger and Trichophyton mentagrophytes at a concentration of 6.25%. Lemon was effective against Fusarium spp. at a concentration of 6.25%. ConclusionsThe hydroalcoholic extracts showed antifungal activity. The in vitro evaluation of medicinal plants showed that the extracts of rue, citronella, and lemon showed a fungicide effect.
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