Miniprobe EUS is a reliable method for validating treatment decisions for patients undergoing minimally invasive procedures for gastric and colonic tumors. This method is particularly valuable in the management of colon cancer, because endoscopic and laparoscopic resections can be offered to selected patients as an alternative to open surgery.

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Endosonography on demand using either miniprobes or conventional endoscopic ultrasound may result in more effective and less invasive staging of esophageal and gastric cancer. Selective use of high-resolution miniprobes and conventional endoscopic ultrasound offers accurate staging of all tumor stages.

Lymphatic mapping and sentinel node biopsy using the radiocolloid technique is feasible in gastric cancer. Limited results indicate a correct prediction of the nodal status and the potential of upstaging.Further studies seem to be justified to evaluate the clinical impact of the method.

With a combined modality treatment, it is possible to achieve excellent local control rates and long-term survival in patients with synovial sarcoma of the extremities. Neoadjuvant treatment can enable limb-sparing surgery in most patients, even if the tumors are located in anatomically difficult areas.

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Nerve damage is still a major concern in all types of surgery and may result in permanent nerve injury. Real time nerve monitoring can reduce the risk of nerve lesions by continuous surveillance of nerve integrity. A stable proximal stimulation of the nerve and recording at the effector organ is essential and the electrodes should not significantly influence the surgical intervention. This work focuses on the simulation of different electrode designs to compare the results considering the application. Four tripolar electrode designs (cuff, flat, cylindrical and open tube) were simulated by finite-element method. The simulations were performed in 3D and quasi-static electromagnetic case considering the metal-electrolyte interface and the anisotropic conductivity of the nerve. Highest nerve stimulation efficiency was found for the closed cuff design followed by the open tube design. Flat and cylindrical designs were similar. Nevertheless each design has advantages in rela tion to implantation method. The advantages and disadvantages of the electrode designs are discussed

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